Galectin-10: a new structural type of prototype galectin dimer and effects on saccharide ligand binding

Abstract Galectin-10 (Gal-10) which forms Charcot-Leyden crystals in vivo, is crucial to regulating lymph cell function. Here, we solved the crystal structures of Gal-10 and eight variants at resolutions of 1.55–2.00 Å. Structural analysis and size exclusion chromatography demonstrated that Gal-10 d...

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Veröffentlicht in:	Glycobiology (Oxford) 2018-03, Vol.28 (3), p.159-168
Hauptverfasser:	Su, Jiyong, Gao, Jin, Si, Yunlong, Cui, Linlin, Song, Chenyang, Wang, Yue, Wu, Runjie, Tai, Guihua, Zhou, Yifa
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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