Tolerance to furfural-induced stress is associated with pentose phosphate pathway genes ZWF1, GND1, RPE1, and TKL1 in Saccharomyces cerevisiae

Engineering yeast to be more tolerant to fermentation inhibitors, furfural and 5-hydroxymethylfurfural (HMF), will lead to more efficient lignocellulose to ethanol bioconversion. To identify target genes involved in furfural tolerance, a Saccharomyces cerevisiae gene disruption library was screened...

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Veröffentlicht in:	Applied microbiology and biotechnology 2006-07, Vol.71 (3), p.339-349
Hauptverfasser:	GORSICH, S. W, DIEN, B. S, NICHOLS, N. N, SLININGER, P. J, LIU, Z. L, SKORY, C. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biotechnology Carbohydrate Epimerases - genetics Carbohydrate Epimerases - metabolism Cellulose - metabolism Ethanol Fermentation Fundamental and applied biological sciences. Psychology Furaldehyde - analogs & derivatives Furaldehyde - pharmacology Gene Expression Regulation, Fungal Genetics Glucosephosphate Dehydrogenase - genetics Glucosephosphate Dehydrogenase - metabolism Heat-Shock Response Lignin - metabolism Mutants Mutation Pentose Phosphate Pathway Proteins Saccharomyces cerevisiae Saccharomyces cerevisiae - drug effects Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - growth & development Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Transketolase - genetics Transketolase - metabolism Yeast Yeasts
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