Gene-environment interaction involved in oral carcinogenesis: molecular epidemiological study for metabolic and DNA repair gene polymorphisms

Background: Exposure to environmental carcinogens leads to oral squamous cell carcinoma (OSCC); however, the impact of genetic variations in carcinogen metabolisms and DNA repair on OSCC risk considering environmental exposures has not been clearly elucidated. Methods: We conducted a case–control...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of oral pathology & medicine 2006-01, Vol.35 (1), p.11-18
Hauptverfasser:	Sugimura, Tomotaka, Kumimoto, Hiroshi, Tohnai, Iwai, Fukui, Takafumi, Matsuo, Keitaro, Tsurusako, Shinichi, Mitsudo, Kenji, Ueda, Minoru, Tajima, Kazuo, Ishizaki, Kanji
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Drinking - adverse effects Biological and medical sciences cancer risk Carcinoma, Squamous Cell - etiology Carcinoma, Squamous Cell - genetics Case-Control Studies Cytochrome P-450 CYP1A1 - genetics Cytochrome P-450 CYP2E1 - genetics DNA Repair - genetics DNA-Binding Proteins - genetics Endonucleases - genetics Environmental Exposure Epidemiologic Studies Female gene-environmental interaction Glutathione Transferase - genetics Humans Male Medical sciences Middle Aged Molecular Epidemiology Mouth Neoplasms - etiology Mouth Neoplasms - genetics oral Otorhinolaryngology. Stomatology polymorphism Polymorphism, Genetic - genetics Risk Factors Smoking - adverse effects Transglutaminases - genetics Xeroderma Pigmentosum Group A Protein - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!