Robust control of the adaptive immune system

•To ensure reproducible function, the immune system must be robust to variability in its cell and molecular components.•Natural variations in αβ T cell response capacity can introduce error into the system and jeopardize reproducibility.•Non-linear control schemes can promote robustness towards thes...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Seminars in immunology 2018-04, Vol.36, p.17-27
Hauptverfasser:	Wong, Harikesh S., Germain, Ronald N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell-to-cell variability Immunology Receptor biophysics Robustness Systems biology αβ T cells
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!