A Novel Protein C-Phycocyanin Plays a Crucial Role in the Hypocholesterolemic Action of Spirulina platensis Concentrate in Rats

This study was designed to clarify the mechanisms of the hypocholesterolemic action of Spirulina platensis concentrate (SPC) and identify the novel hypocholesterolemic protein derived from SPC. We investigated the effects of casein or SPC on the solubility of cholesterol, taurocholate binding capaci...

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Veröffentlicht in:	The Journal of nutrition 2005-10, Vol.135 (10), p.2425-2430
Hauptverfasser:	Nagaoka, Satoshi, Shimizu, Kazuo, Kaneko, Hideki, Shibayama, Fumi, Morikawa, Kensei, Kanamaru, Yoshihiro, Otsuka, Ayako, Hirahashi, Tomohiro, Kato, Toshimitsu
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetone Algae animal models Animals Anticholesteremic Agents - pharmacology Bacterial Proteins bile acids binding capacity Biological and medical sciences blood lipids C-phycocyanin Caco-2 Cells casein Caseins - pharmacokinetics cholesteremic effect Cholesterol Cholesterol - pharmacokinetics cholesterol metabolism Cholesterol, Dietary - pharmacokinetics cultured cells Cyanobacteria feces Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Humans Hypercholesterolemia - drug therapy Hypercholesterolemia - metabolism In Vitro Techniques liver Male Metabolism Micelles Phycocyanin - pharmacology Proteins rat Rats Rats, Wistar Rodents single cell protein Solubility Solvents Spirulina Spirulina platensis Taurocholic Acid - metabolism Toxicity uptake mechanisms Vertebrates: anatomy and physiology, studies on body, several organs or systems
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