Microfluidics: A high-throughput system for the assessment of the endotheliopathy of trauma and the effect of timing of plasma administration on ameliorating shock-associated endothelial dysfunction

Early resuscitation after trauma-hemorrhagic shock with plasma rather than crystalloid may ameliorate systemic endothelial cell (EC) injury and dysfunction (endotheliopathy of trauma). We postulated that endothelial-lined microfluidic networks would be a useful platform to study the EC activation/in...

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Veröffentlicht in:The journal of trauma and acute care surgery 2018-04, Vol.84 (4), p.575-582
Hauptverfasser: Diebel, Lawrence N, Martin, Jonathan V, Liberati, David M
Format: Artikel
Sprache:eng
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