Preclinical evaluation of an 18F-trifluoroborate methionine derivative for glioma imaging

Purpose 11 C–methionine (MET) is one of the most commonly used amino acid tracers for PET imaging of brain tumors. In this study, we report an 18 F-labeled boron-derived methionine analogue, denoted as 18 F-B-MET, as a potential substitute of 11 C–MET for glioma PET imaging. Methods 19 F-B-MET was s...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2018-04, Vol.45 (4), p.585-592
Hauptverfasser:	Yang, Xiangyu, Liu, Zhibo, Zhang, Huimin, Li, Zhu, Munasinghe, Jeeva P., Niu, Gang, Teng, Gaojun, Chen, Xiaoyuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Boron Brain Brain cancer Brain tumors Cardiology Fluorides Glioma High-performance liquid chromatography Imaging In vivo methods and tests Incubation Injection Labeling Liquid chromatography Medicine Medicine & Public Health Methionine Neuroimaging Nuclear Medicine Oncology Original Article Orthopedics Pharmacology Positron emission Positron emission tomography Quality control Radiology Tomography Tracers Tumor cells Tumors Xenografts
Online-Zugang:	Volltext
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