Omitting cytogenetic assessment from routine treatment response monitoring in chronic myeloid leukemia is safe

Objectives The monitoring of response in chronic myeloid leukemia (CML) is of great importance to identify patients failing their treatment in order to adjust TKI choice and thereby prevent progression to advanced stage disease. Cytogenetic monitoring has a lower sensitivity, is expensive, and requi...

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Veröffentlicht in:	European journal of haematology 2018-04, Vol.100 (4), p.367-371
Hauptverfasser:	Geelen, Inge G.P., Thielen, Noortje, Janssen, Jeroen J.W.M., Hoogendoorn, Mels, Roosma, Tanja J.A., Valk, Peter J.M., Visser, Otto, Cornelissen, Jan J., Westerweel, Peter E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone marrow Chronic myeloid leukemia Cytogenetics Invasiveness Leukemia molecular cytogenetics Myeloid leukemia myeloproliferative neoplasms Patients philadelphia chromosome Sampling
Online-Zugang:	Volltext
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