PKA‐binding domain of AKAP8 is essential for direct interaction with DPY30 protein

The main function of the A kinase‐anchoring proteins (AKAPs) is to target the cyclic AMP‐dependent protein kinase A (PKA) to its cellular substrates through the interaction with its regulatory subunits. Besides anchoring of PKA, AKAP8 participates in regulating the histone H3 lysine 4 (H3K4) histone...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The FEBS journal 2018-03, Vol.285 (5), p.947-964
Hauptverfasser:	Bieluszewska, Anna, Weglewska, Martyna, Bieluszewski, Tomasz, Lesniewicz, Krzysztof, Poreba, Elzbieta
Format:	Artikel
Sprache:	eng
Schlagworte:	A kinase-anchoring protein AKAP8 AKAP8L Alternative splicing Amino acid substitution Anchoring Apoptosis Binding Brefeldin A Chromatin Cyclic AMP Deoxyribonucleic acid Dimerization DNA DNA biosynthesis DPY30 Gene silencing Guanine H3K4 HMT complexes H3K4 methylation Histone H3 Histone methyltransferase Homology Kinases Lysine Mitosis PKA regulatory subunit Protein kinase A Proteins Regulatory subunits rRNA Substrates
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!