IL‐1α inhibits proliferation and adipogenic differentiation of human adipose‐derived mesenchymal stem cells through NF‐κB‐ and ERK1/2‐mediated proinflammatory cytokines

Dysfunctional adipogenesis such as subcutaneous lipoatrophy is closely related to insulin resistance and metabolic disorders. Although the expression or release of the cytokine interleukin‐1α (IL‐1α) is known to increase in adipose tissue in response to cell death, cell senescence, aging, or solar r...

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Veröffentlicht in:Cell biology international 2018-07, Vol.42 (7), p.794-803
Hauptverfasser: Sun, Xuerong, Zou, Tangbin, Zuo, Changqing, Zhang, Mingmeng, Shi, Benyan, Jiang, Zhiwen, Cui, Hongjing, Liao, Xiaoxin, Li, Xiaoyi, Tang, Yuelian, Liu, Yusheng, Liu, Xinguang
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