Synthesis and Antibacterial Activity of Quaternary Ammonium Salt-Type Antibacterial Agents with a Phosphate Group

Quaternary ammonium salts are frequently used as antibacterial agent that disrupts cell membrane through the binding of their ammonium cations to anionic sites in the outer layer tissue of bacteria. This article describes the synthesis of quaternary ammonium salt-type antibacterial agents with a pho...

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Veröffentlicht in:	Journal of Oleo Science 2008, Vol.57(8), pp.445-452
Hauptverfasser:	Ohta, Yumi, Kondo, Yukishige, Kawada, Kazuo, Teranaka, Toshio, Yoshino, Norio
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - pharmacology antibacterial agent Antifungal Agents - chemical synthesis Antifungal Agents - pharmacology Binding Sites Bromides - chemistry Bromides - metabolism Cell Membrane - chemistry Cell Membrane - metabolism Durapatite - chemistry Durapatite - metabolism Fungi - drug effects Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects Microbial Sensitivity Tests minimum inhibitory concentration phosphate group Phosphates - chemistry Phosphates - metabolism Quaternary Ammonium Compounds - chemical synthesis Quaternary Ammonium Compounds - pharmacology quaternary ammonium salt Structure-Activity Relationship synthesis
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