Fluid Mixing for Low‐Power ‘Digital Microfluidics’ Using Electroactive Molecular Monolayers
A switchable electrode, which relies on an indium‐tin oxide conductive substrate coated with a self‐assembled monolayer terminated with an anthraquinone group (AQ), is reported as an electrowetting system. AQ electrochemical features confer the capability of yielding a significant modulation of surf...
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| Veröffentlicht in: | Small (Weinheim an der Bergstrasse, Germany) Germany), 2018-03, Vol.14 (10), p.n/a |
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| container_title | Small (Weinheim an der Bergstrasse, Germany) |
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| creator | Maglione, Maria Serena Casalini, Stefano Georgakopoulos, Stamatis Barbalinardo, Marianna Parkula, Vitaliy Crivillers, Núria Rovira, Concepció Greco, Pierpaolo Mas‐Torrent, Marta |
| description | A switchable electrode, which relies on an indium‐tin oxide conductive substrate coated with a self‐assembled monolayer terminated with an anthraquinone group (AQ), is reported as an electrowetting system. AQ electrochemical features confer the capability of yielding a significant modulation of surface wettability as high as 26° when its redox state is switched. Hence, an array of planar electrodes for droplets actuation is fabricated and integrated in a microfluidic device to perform mixing and dispensing on sub‐nanoliter scale. Vehiculation of cells across microfluidic compartments is made possible by taking full advantage of surface electrowetting in culture medium.
An array of planar indium‐tin oxide electrodes for droplets actuation based on a self‐assembled monolayer terminated with a switchable electroactive anthraquinone group is fabricated. The electrodes are integrated in a microfluidic device to perform mixing and dispensing at sub‐nanoliter scale. Vehiculation of cells across microfluidic compartments is further demonstrated. |
| doi_str_mv | 10.1002/smll.201703344 |
| format | Article |
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An array of planar indium‐tin oxide electrodes for droplets actuation based on a self‐assembled monolayer terminated with a switchable electroactive anthraquinone group is fabricated. The electrodes are integrated in a microfluidic device to perform mixing and dispensing at sub‐nanoliter scale. Vehiculation of cells across microfluidic compartments is further demonstrated.</description><identifier>ISSN: 1613-6810</identifier><identifier>EISSN: 1613-6829</identifier><identifier>DOI: 10.1002/smll.201703344</identifier><identifier>PMID: 29280286</identifier><language>eng</language><publisher>Germany: Wiley Subscription Services, Inc</publisher><subject>Actuation ; Coated electrodes ; Dispensing ; electroactive molecule ; electrowetting ; Microfluidics ; Monolayers ; Nanotechnology ; quinone ; self‐assembled monolayer ; Substrates ; Tin oxides ; Wettability</subject><ispartof>Small (Weinheim an der Bergstrasse, Germany), 2018-03, Vol.14 (10), p.n/a</ispartof><rights>2017 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><rights>2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.</rights><rights>2018 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4134-fb1b5a34ac884812c00d71ca9a92d325dc407a43330e27301b90d1c230a630103</citedby><cites>FETCH-LOGICAL-c4134-fb1b5a34ac884812c00d71ca9a92d325dc407a43330e27301b90d1c230a630103</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fsmll.201703344$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fsmll.201703344$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27915,27916,45565,45566</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29280286$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Maglione, Maria Serena</creatorcontrib><creatorcontrib>Casalini, Stefano</creatorcontrib><creatorcontrib>Georgakopoulos, Stamatis</creatorcontrib><creatorcontrib>Barbalinardo, Marianna</creatorcontrib><creatorcontrib>Parkula, Vitaliy</creatorcontrib><creatorcontrib>Crivillers, Núria</creatorcontrib><creatorcontrib>Rovira, Concepció</creatorcontrib><creatorcontrib>Greco, Pierpaolo</creatorcontrib><creatorcontrib>Mas‐Torrent, Marta</creatorcontrib><title>Fluid Mixing for Low‐Power ‘Digital Microfluidics’ Using Electroactive Molecular Monolayers</title><title>Small (Weinheim an der Bergstrasse, Germany)</title><addtitle>Small</addtitle><description>A switchable electrode, which relies on an indium‐tin oxide conductive substrate coated with a self‐assembled monolayer terminated with an anthraquinone group (AQ), is reported as an electrowetting system. AQ electrochemical features confer the capability of yielding a significant modulation of surface wettability as high as 26° when its redox state is switched. Hence, an array of planar electrodes for droplets actuation is fabricated and integrated in a microfluidic device to perform mixing and dispensing on sub‐nanoliter scale. Vehiculation of cells across microfluidic compartments is made possible by taking full advantage of surface electrowetting in culture medium.
An array of planar indium‐tin oxide electrodes for droplets actuation based on a self‐assembled monolayer terminated with a switchable electroactive anthraquinone group is fabricated. The electrodes are integrated in a microfluidic device to perform mixing and dispensing at sub‐nanoliter scale. Vehiculation of cells across microfluidic compartments is further demonstrated.</description><subject>Actuation</subject><subject>Coated electrodes</subject><subject>Dispensing</subject><subject>electroactive molecule</subject><subject>electrowetting</subject><subject>Microfluidics</subject><subject>Monolayers</subject><subject>Nanotechnology</subject><subject>quinone</subject><subject>self‐assembled monolayer</subject><subject>Substrates</subject><subject>Tin oxides</subject><subject>Wettability</subject><issn>1613-6810</issn><issn>1613-6829</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNqFkE1PAjEQhhujEUSvHs0mXryA0w_242gQ1GSJJsq5Kd0uKSkUW1bkxk_wqH-PX2IJiIkXTzOTPPNO-yB0jqGFAci1nxjTIoAToJSxA1THMabNOCXZ4b7HUEMn3o8BKCYsOUY1kpEUSBrXkeiZShdRX7_r6SgqrYtyu1ivPp7sQrlovfq81SM9FyYQ0tlyA2vp16uvaOA3G12j5NxZIef6TUV9G8bKCBe6qTViqZw_RUelMF6d7WoDDXrdl859M3-8e-jc5E3JMGXNcoiHbUGZkGnKUkwkQJFgKTKRkYKSdiEZJIJRSkGRhAIeZlBgSSiIOExAG-hqmztz9rVSfs4n2ktljJgqW3mOsyCizZJ2HNDLP-jYVm4aXseDShzTLA13Gqi1pcLHvXeq5DOnJ8ItOQa-kc838vlefli42MVWw4kq9viP7QBkW2ChjVr-E8ef-3n-G_4NPBCSog</recordid><startdate>201803</startdate><enddate>201803</enddate><creator>Maglione, Maria Serena</creator><creator>Casalini, Stefano</creator><creator>Georgakopoulos, Stamatis</creator><creator>Barbalinardo, Marianna</creator><creator>Parkula, Vitaliy</creator><creator>Crivillers, Núria</creator><creator>Rovira, Concepció</creator><creator>Greco, Pierpaolo</creator><creator>Mas‐Torrent, Marta</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><scope>7X8</scope></search><sort><creationdate>201803</creationdate><title>Fluid Mixing for Low‐Power ‘Digital Microfluidics’ Using Electroactive Molecular Monolayers</title><author>Maglione, Maria Serena ; Casalini, Stefano ; Georgakopoulos, Stamatis ; Barbalinardo, Marianna ; Parkula, Vitaliy ; Crivillers, Núria ; Rovira, Concepció ; Greco, Pierpaolo ; Mas‐Torrent, Marta</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4134-fb1b5a34ac884812c00d71ca9a92d325dc407a43330e27301b90d1c230a630103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Actuation</topic><topic>Coated electrodes</topic><topic>Dispensing</topic><topic>electroactive molecule</topic><topic>electrowetting</topic><topic>Microfluidics</topic><topic>Monolayers</topic><topic>Nanotechnology</topic><topic>quinone</topic><topic>self‐assembled monolayer</topic><topic>Substrates</topic><topic>Tin oxides</topic><topic>Wettability</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Maglione, Maria Serena</creatorcontrib><creatorcontrib>Casalini, Stefano</creatorcontrib><creatorcontrib>Georgakopoulos, Stamatis</creatorcontrib><creatorcontrib>Barbalinardo, Marianna</creatorcontrib><creatorcontrib>Parkula, Vitaliy</creatorcontrib><creatorcontrib>Crivillers, Núria</creatorcontrib><creatorcontrib>Rovira, Concepció</creatorcontrib><creatorcontrib>Greco, Pierpaolo</creatorcontrib><creatorcontrib>Mas‐Torrent, Marta</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Small (Weinheim an der Bergstrasse, Germany)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Maglione, Maria Serena</au><au>Casalini, Stefano</au><au>Georgakopoulos, Stamatis</au><au>Barbalinardo, Marianna</au><au>Parkula, Vitaliy</au><au>Crivillers, Núria</au><au>Rovira, Concepció</au><au>Greco, Pierpaolo</au><au>Mas‐Torrent, Marta</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fluid Mixing for Low‐Power ‘Digital Microfluidics’ Using Electroactive Molecular Monolayers</atitle><jtitle>Small (Weinheim an der Bergstrasse, Germany)</jtitle><addtitle>Small</addtitle><date>2018-03</date><risdate>2018</risdate><volume>14</volume><issue>10</issue><epage>n/a</epage><issn>1613-6810</issn><eissn>1613-6829</eissn><abstract>A switchable electrode, which relies on an indium‐tin oxide conductive substrate coated with a self‐assembled monolayer terminated with an anthraquinone group (AQ), is reported as an electrowetting system. AQ electrochemical features confer the capability of yielding a significant modulation of surface wettability as high as 26° when its redox state is switched. Hence, an array of planar electrodes for droplets actuation is fabricated and integrated in a microfluidic device to perform mixing and dispensing on sub‐nanoliter scale. Vehiculation of cells across microfluidic compartments is made possible by taking full advantage of surface electrowetting in culture medium.
An array of planar indium‐tin oxide electrodes for droplets actuation based on a self‐assembled monolayer terminated with a switchable electroactive anthraquinone group is fabricated. The electrodes are integrated in a microfluidic device to perform mixing and dispensing at sub‐nanoliter scale. Vehiculation of cells across microfluidic compartments is further demonstrated.</abstract><cop>Germany</cop><pub>Wiley Subscription Services, Inc</pub><pmid>29280286</pmid><doi>10.1002/smll.201703344</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Actuation Coated electrodes Dispensing electroactive molecule electrowetting Microfluidics Monolayers Nanotechnology quinone self‐assembled monolayer Substrates Tin oxides Wettability |
| title | Fluid Mixing for Low‐Power ‘Digital Microfluidics’ Using Electroactive Molecular Monolayers |
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