Mg–Al and Zn–Al Layered Double Hydroxides Promote Dynamic Expression of Marker Genes in Osteogenic Differentiation by Modulating Mitogen‐Activated Protein Kinases

The effect of LDH samples comprised of chloride anions intercalated between positive layers of magnesium/aluminum (Mg‐Al LDH) or zinc/aluminum (Zn‐Al LDH) chemical composition on pre‐osteoblast performance is investigated. Non‐cytotoxic concentrations of both LDHs modulated pre‐osteoblast adhesion b...

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Veröffentlicht in:	Advanced healthcare materials 2018-02, Vol.7 (4), p.n/a
Hauptverfasser:	Kang, Ha Ram, da Costa Fernandes, Célio Junior, da Silva, Rodrigo Augusto, Constantino, Vera Regina Leopoldo, Koh, Ivan Hong Jun, Zambuzzi, Willian F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline phosphatase Aluminum Anions Biocompatibility Biomedical materials Bone diseases Bone grafts Bone healing Bone remodeling Bone sialoprotein Cbfa-1 protein Cofilin Cytoskeleton Cytotoxicity differentiation Differentiation (biology) double metal hydroxides Drug delivery systems Extracellular signal-regulated kinase Gene expression Genes hydrotalcite‐like materials Hydroxides JNK protein Kinases layered double hydroxides Magnesium MAP kinase Nanomaterials nanoparticles Nanotechnology Osteoblastogenesis Osteoblasts Osteoclastogenesis Osteoprotegerin Phosphatase Phosphoprotein phosphatase Protein kinase Protein phosphatase Proteins Signaling TRANCE protein Zinc
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