Terfenadine-induced apoptosis in human melanoma cells is mediated through Ca super(2+) homeostasis modulation and tyrosine kinase activity, independently of H1 histamine receptors

In our previous works, we have demonstrated that terfenadine (TEF) induces DNA damage and apoptosis in human melanoma cell lines. In this present work, we have studied the effect of histamine on viability of A375 human melanoma cells and the cell-signalling pathways through which TEF may induce its...

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Veröffentlicht in:	Carcinogenesis (New York) 2008-03, Vol.29 (3), p.500-509
Hauptverfasser:	Jangi, Shawkat-Muhialdin, Ruiz-Larrea, MBegona, Nicolau-Galmes, Francesca, Andollo, Noelia, Arroyo-Berdugo, Yoana, Ortega-Martinez, Idoia, Diaz-Perez, Jose Luis, Boyano, Maria D
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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