Chemotherapy Immunophenoprofiles in Non‐Small‐Cell Lung Cancer by Personalized Membrane Proteomics

Objectives: No study has addressed how the immune status at the molecular level is affected by first‐line pemetrexed and cisplatin (PEM–CIS) combination therapy in patients with non‐small‐cell lung cancer (NSCLC). Thus, we aimed to identify the immune status from membrane proteome alterations in pat...

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Veröffentlicht in:	Proteomics. Clinical applications 2018-03, Vol.12 (2), p.n/a
Hauptverfasser:	Putri, Denise Utami, Feng, Po‐Hao, Hsu, Yuu‐Hueih, Lee, Kang‐Yun, Jiang, Feng‐Wen, Kuo, Lu‐Wei, Chen, Yu‐Ju, Han, Chia‐Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Aged Antigen presentation Antigens Cancer Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - immunology Carcinoma, Non-Small-Cell Lung - metabolism Cell Membrane - metabolism Chemotherapy Cisplatin Cytotoxicity Female Humans Immune status Immunoregulation Leukocytes (mononuclear) Leukocytes (neutrophilic) Leukocytes, Mononuclear - metabolism Lung cancer Lung Neoplasms - drug therapy Lung Neoplasms - immunology Lung Neoplasms - metabolism Lymphocytes Lymphocytes T Major histocompatibility complex Male Membrane Proteins - metabolism Middle Aged Non-small cell lung carcinoma non‐small‐cell lung cancer Patients Peripheral blood mononuclear cells personalized membrane proteomics Phenotype Phenotypes Population studies Proteins Proteomics Proteomics - methods Signaling T cell receptors
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