Current ideas of a complex relationship between atrial fibrillation and ischemic heart disease and of optimum tactics for anticoagulant therapy to prevent embolism in systemic circulation

The article discusses the issue of searching for optimum oral anticoagulants to prevent thrombosis and embolism induced by heart disease both in patients with atrial fibrillation and sinus rhythm. A complex bidirectional relationship between atrial fibrillation and coronary atherosclerosis is consid...

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Veröffentlicht in:Kardiologiia 2017-01, Vol.57 (S1), p.312-322
Hauptverfasser: Golshmid, M V, Gilyarevskiy, S R, Kuzmina, I M, Sinitsina, I I
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container_title Kardiologiia
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creator Golshmid, M V
Gilyarevskiy, S R
Kuzmina, I M
Sinitsina, I I
description The article discusses the issue of searching for optimum oral anticoagulants to prevent thrombosis and embolism induced by heart disease both in patients with atrial fibrillation and sinus rhythm. A complex bidirectional relationship between atrial fibrillation and coronary atherosclerosis is considered along with possible mechanisms for development of myocardial infarction in patients with atrial fibrillation. The authors provided evidence-based data which can be used in selecting an anticoagulant for prevention of heart disease induced thrombosis and embolism taking into account both the efficacy and safety established in randomized clinical studies.
doi_str_mv 10.18087/cardio.2399
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subjects Anticoagulants - administration & dosage
Anticoagulants - therapeutic use
Atrial Fibrillation - complications
Atrial Fibrillation - physiopathology
Coronary Artery Disease - complications
Coronary Artery Disease - physiopathology
Embolism - etiology
Embolism - prevention & control
Humans
Myocardial Infarction - etiology
Myocardial Ischemia - complications
Myocardial Ischemia - physiopathology
title Current ideas of a complex relationship between atrial fibrillation and ischemic heart disease and of optimum tactics for anticoagulant therapy to prevent embolism in systemic circulation
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