Current ideas of a complex relationship between atrial fibrillation and ischemic heart disease and of optimum tactics for anticoagulant therapy to prevent embolism in systemic circulation
The article discusses the issue of searching for optimum oral anticoagulants to prevent thrombosis and embolism induced by heart disease both in patients with atrial fibrillation and sinus rhythm. A complex bidirectional relationship between atrial fibrillation and coronary atherosclerosis is consid...
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Veröffentlicht in: | Kardiologiia 2017-01, Vol.57 (S1), p.312-322 |
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creator | Golshmid, M V Gilyarevskiy, S R Kuzmina, I M Sinitsina, I I |
description | The article discusses the issue of searching for optimum oral anticoagulants to prevent thrombosis and embolism induced by heart disease both in patients with atrial fibrillation and sinus rhythm. A complex bidirectional relationship between atrial fibrillation and coronary atherosclerosis is considered along with possible mechanisms for development of myocardial infarction in patients with atrial fibrillation. The authors provided evidence-based data which can be used in selecting an anticoagulant for prevention of heart disease induced thrombosis and embolism taking into account both the efficacy and safety established in randomized clinical studies. |
doi_str_mv | 10.18087/cardio.2399 |
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subjects | Anticoagulants - administration & dosage Anticoagulants - therapeutic use Atrial Fibrillation - complications Atrial Fibrillation - physiopathology Coronary Artery Disease - complications Coronary Artery Disease - physiopathology Embolism - etiology Embolism - prevention & control Humans Myocardial Infarction - etiology Myocardial Ischemia - complications Myocardial Ischemia - physiopathology |
title | Current ideas of a complex relationship between atrial fibrillation and ischemic heart disease and of optimum tactics for anticoagulant therapy to prevent embolism in systemic circulation |
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