Plasma Membrane Properties Involved in the Photodynamic Efficacy of Merocyanine 540 and Tetrasulfonated Aluminum Phthalocyanine

Merocyanine 540 (MC540)-mediated photodynamic damage to erythrocytes was strongly reduced when illumination was performed at pH 8.5 as compared to pH 7.4. This could be explained by high pH-mediated hyperpolarization of the erythrocyte membrane, resulting in decreased MC540 binding at pH 8.5. In acc...

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