Synthesis of p-amino-WNA derivatives to enhance the stability of the anti-parallel triplex

We have previously developed W-shaped nucleoside analogs (WNAs) having a nucleobase and an aromatic ring for the formation of the unnatural triplex DNA. Modification of an aromatic ring of WNA is highly effective regarding the stability of the triplex DNA. In this study, we designed new WNA analogs...

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Veröffentlicht in:	Tetrahedron 2008-07, Vol.64 (30), p.7164-7170
Hauptverfasser:	Taniguchi, Yosuke, Togo, Mieko, Aoki, Eriko, Uchida, Yuko, Sasaki, Shigeki
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigene Non-natural type triplex DNA Nucleoside analogs Rearrangement
Online-Zugang:	Volltext
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