UBE2C is involved in the functions of ECRG4 on esophageal squamous cell carcinoma

Esophageal cancerrelated gene 4 (ECRG4) is down-regulated in esophageal squamous-cell carcinoma (ESCC) and inhibits the tumorigenicity of ESCC cells. Ubiquitin conjugating enzyme E2 (UBE2C), an E2 ubiquitin-conjugating enzyme, is upregulated in numerous human cancers, including ESCC. mRNA and protei...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2018-02, Vol.98, p.201-206
Hauptverfasser:	Li, Linwei, Li, Xiaoyan, Wang, Wenyu, Gao, Tianhui, Shi, Zuxuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biomarkers, Tumor - biosynthesis Biomarkers, Tumor - genetics Carcinoma, Squamous Cell - metabolism Cell Line, Tumor Cell Proliferation - physiology Esophageal Neoplasms - metabolism Esophageal Squamous Cell Carcinoma Humans Neoplasm Proteins - biosynthesis Neoplasm Proteins - genetics NF-κB Proliferation Ubiquitin-Conjugating Enzymes - antagonists & inhibitors Ubiquitin-Conjugating Enzymes - biosynthesis Ubiquitin-Conjugating Enzymes - genetics
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