Interleukin-37 alleviates airway inflammation and remodeling in asthma via inhibiting the activation of NF-κB and STAT3 signalings

Asthma is a common respiratory inflammatory disorder disease of childhood, and airway smooth muscle cells (ASMCs) play an important role in this disease. Recently, studies have found that interleukin (IL)-37 inhibits allergic airway inflammation of asthmatic mouse models. The aim of this study was t...

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Veröffentlicht in:International immunopharmacology 2018-02, Vol.55, p.198-204
Hauptverfasser: Huang, Nina, Liu, Kebei, Liu, Jianping, Gao, Xiaopeng, Zeng, Zhu, Zhang, Yudan, Chen, Jing
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Sprache:eng
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