Suppression of Disheveled–Axin Domain Containing 1 (DIXDC1) by MicroRNA-186 Inhibits the Proliferation and Invasion of Retinoblastoma Cells

Recent evidence shows that Disheveled–Axin domain containing 1 (DIXDC1) is dysregulated in various cancers. However, the role of DIXDC1 in retinoblastoma (RB) remains unclear. In this study, we aimed to investigate the biological function of DIDXDC1 in RB and the way in which its expression is regul...

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Veröffentlicht in:	Journal of molecular neuroscience 2018-02, Vol.64 (2), p.252-261
Hauptverfasser:	Che, Xuanyi, Qian, Yuanjie, Li, Di
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antitumor activity Biomedical and Life Sciences Biomedicine Biotechnology Cancer Cancer therapies Cell Biology Cell Line Cell Line, Tumor Cell Movement Cell Proliferation Gene expression Hospitals Humans Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Microfilament Proteins - genetics Microfilament Proteins - metabolism MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miRNA Neurochemistry Neurology Neurosciences Pathogenesis Polymerase chain reaction Proteins Proteomics Retina Retinoblastoma Retinoblastoma - metabolism Ribonucleic acid RNA Signaling siRNA Target recognition Tumors Wnt protein Wnt Signaling Pathway
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