Enantiopurity and absolute configuration determination of arene cis‐dihydrodiol metabolites and derivatives using chiral boronic acids

The relative merits of the methods employed to determine enantiomeric excess (ee) values and absolute configurations of chiral arene and alkene cis‐1,2‐diol metabolites, including boronate formation, using racemic or enantiopure (+) and (−)‐2‐(1‐methoxyethyl)phenylboronic acid (MEPBA), are discussed...

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Veröffentlicht in:	Chirality (New York, N.Y.) N.Y.), 2018-01, Vol.30 (1), p.5-18
Hauptverfasser:	Boyd, Derek R., Sharma, Narain D., Goodrich, Peter A., Malone, John F., McConville, Gareth, Harrison, John S., Stevenson, Paul J., Allen, Christopher C.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absolute configuration Acids Alkenes asymmetric synthesis bacterial metabolism boronate diastereomers boronic acid enantiomers Catechol cis‐1,2‐diol bioproducts Configurations enantiomeric excess values Metabolites Reagents
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