Synthesis and biological evaluation of novel doxorubicin-containing ASGP-R-targeted drug-conjugates

[Display omitted] Asialoglycoprotein receptor (ASGP-R) belongs to a wide family of C-type lectins and it is currently regarded as an attractive protein in the field of targeted drug delivery (TDD). It is abundantly expressed in hepatocytes and can be found predominantly on the sinusoidal surface esp...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2018-02, Vol.28 (3), p.503-508
Hauptverfasser:	Ivanenkov, Yan A., Majouga, Alexander G., Petrov, Rostislav A., Petrov, Stanislav A., Kovalev, Sergey V., Maklakova, Svetlana Yu, Yamansarov, Emil Yu, Saltykova, Irina V., Deyneka, Ekaterina V., Filkov, Gleb I., Kotelianski, Victor E., Zatsepin, Timofey S., Beloglazkina, Elena K.
Format:	Artikel
Sprache:	eng
Schlagworte:	ASGP-R Cancer Doxorubicin Targeted drug delivery
Online-Zugang:	Volltext
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