Identification of Drug Candidates to Suppress Cigarette Smoke-induced Inflammation via Connectivity Map Analyses

Cigarette smoking is the main risk factor for chronic obstructive pulmonary disease, and to date, existing pharmacologic interventions have been ineffective at controlling inflammatory processes associated with the disease. To address this issue, we used the Connectivity Map (cMap) database to ident...

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Veröffentlicht in:American journal of respiratory cell and molecular biology 2018-06, Vol.58 (6), p.727-735
Hauptverfasser: Vanderstocken, Gilles, Dvorkin-Gheva, Anna, Shen, Pamela, Brandsma, Corry-Anke, Obeidat, Ma'en, Bossé, Yohan, Hassell, John A, Stampfli, Martin R
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Sprache:eng
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