Co-localization of cystatin C and prosaposin in cultured neurons and in anterior horn neurons with amyotrophic lateral sclerosis

Cystatin C (CST3) is a cysteine protease inhibitor that regulates lysosomal enzyme activity and is reported to be involved in the process of neurodegeneration. In the present study, we investigated whether CST3 interacts with other proteins and affects neurodegeneration in vitro and under disease co...

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Veröffentlicht in:	Journal of the neurological sciences 2018-01, Vol.384, p.67-74
Hauptverfasser:	Wada, Yasuko, Nagai, Atsushi, Sheikh, Abdullah Md, Onoda, Keiichi, Terashima, Masaharu, Shiota, Yuri, Araki, Asuka, Yamaguchi, Shuhei
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyotrophic lateral sclerosis Cathepsin B Cystatin C Lipofuscin Prosaposin
Online-Zugang:	Volltext
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