Limonia acidissima L. leaf mediated synthesis of silver and zinc oxide nanoparticles and their antibacterial activities

Green chemistry is a novel method for the synthesis of silver and zinc oxide nanoparticles. The present investigation focused on synthesis of biogenic silver and zinc oxide nanoparticles. They were assayed for their antibacterial activities against test bacterial species. The results revealed that the silver nanoparticles showed the maximum zone of inhibition 15.16, 15.5 and 13.33 mm at 400 μg/mL to S. aureus, S. typhi and P. aeruginosa respectively, when compared to the Erythromycin. While zinc oxide nanoparticles showed less activity in comparison to silver nanoparticles owing to the agglomeration of nanoparticles. It is evident from our investigation that silver nanoparticles could be used as an antimicrobial due to their intrinsic properties in biomedical application and food packing industries. •L. acidissima is used for synthesis of AgNPs & ZnONPs.•Comparative assay of antimicrobial activity of AgNPs & ZnONPs.•AgNPs shows the greater zone of inhibition as compared to Erythromycin.•Caveolae mediated endocytosis.•DNA damage, disruption of membrane morphology leading to death of bacteria.