Virus stamping for targeted single-cell infection in vitro and in vivo

Viruses are transduced to single cells in tissues, organoids and in the mouse brain using mechanical carriers. Genetic engineering by viral infection of single cells is useful to study complex systems such as the brain. However, available methods for infecting single cells have drawbacks that limit...

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Veröffentlicht in:	Nature biotechnology 2018-01, Vol.36 (1), p.81-88
Hauptverfasser:	Schubert, Rajib, Trenholm, Stuart, Balint, Kamill, Kosche, Georg, Cowan, Cameron S, Mohr, Manuel A, Munz, Martin, Martinez-Martin, David, Fläschner, Gotthold, Newton, Richard, Krol, Jacek, Scherf, Brigitte Gross, Yonehara, Keisuke, Wertz, Adrian, Ponti, Aaron, Ghanem, Alexander, Hillier, Daniel, Conzelmann, Karl-Klaus, Müller, Daniel J, Roska, Botond
Format:	Artikel
Sprache:	eng
Schlagworte:	13 14 14/19 14/28 14/34 14/35 14/69 42/44 45 631/1647/2300 631/378/87 631/61/350 631/80 64 64/60 Agriculture Bioinformatics Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Biotechnology Brain Calcium Cell culture Complex systems Fluorescence Fluorescent indicators Genetic engineering Health aspects Herpes simplex Infections Life Sciences Nanoparticles Organoids Rabies Retina Stamping Viral infections Virus diseases Viruses
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