Soluble expression, purification and functional identification of a disulfide-rich conotoxin derived from Conus litteratus

Conotoxins are a diverse array of small peptides mostly with multiple disulfide bridges. These peptides become an increasing significant source of neuro-pharmacological probes and drugs as a result of the high selectivity for ion channels and receptors. Usually, the analogue of natural conotoxins is...

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Veröffentlicht in:Journal of biotechnology 2007-01, Vol.128 (1), p.184-193
Hauptverfasser: Pi, Canhui, Liu, Junliang, Wang, Lei, Jiang, Xiuhua, Liu, Yun, Peng, Can, Chen, Shangwu, Xu, Anlong
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Sprache:eng
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