Sweet! Helicobacter Sugar Calms Intestinal Macrophages

Sweet! Helicobacter Sugar Calms Intestinal Macrophages

In the absence of IL-10, Helicobacter hepaticus (Hh) induces colitis. In this issue of Cell Host & Microbe, Danne et al. (2017) report that Hh produces a polysaccharide that induces an anti-inflammatory response in macrophages, providing a potential clue as to why this bacterium is normally tole...

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Veröffentlicht in:Cell host & microbe 2017-12, Vol.22 (6), p.719-721
Hauptverfasser: Bain, Calum C., Kullberg, Marika C.
Format: Artikel
Sprache:eng
Schlagworte:
Colitis - immunology
Helicobacter - immunology
Helicobacter Infections - immunology
Interleukin-10 - immunology
Macrophages - immunology
Sugars
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Kullberg, Marika C.
description In the absence of IL-10, Helicobacter hepaticus (Hh) induces colitis. In this issue of Cell Host & Microbe, Danne et al. (2017) report that Hh produces a polysaccharide that induces an anti-inflammatory response in macrophages, providing a potential clue as to why this bacterium is normally tolerated by the immune system. In the absence of IL-10, Helicobacter hepaticus (Hh) induces colitis. In this issue of Cell Host & Microbe, Danne et al. (2017) report that Hh produces a polysaccharide that induces an anti-inflammatory response in macrophages, providing a potential clue as to why this bacterium is normally tolerated by the immune system.
doi_str_mv 10.1016/j.chom.2017.11.014
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subjects Colitis - immunology
Helicobacter - immunology
Helicobacter Infections - immunology
Interleukin-10 - immunology
Macrophages - immunology
Sugars
title Sweet! Helicobacter Sugar Calms Intestinal Macrophages
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