Alkaloid profile and antimicrobial activity of Lupinus angustifolius L. alkaloid extract
Purpose of the present study was to evaluate alkaloid profile of the aerial parts of Lupinus angustifolius growing in Turkey by capillary gas chromatography-mass spectrometry (GC-MS). Fifteen alkaloids were identified by capillary GC-MS. 13α-Hydroxylupanine (50.78%) and lupanine (23.55%) were determ...
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| Veröffentlicht in: | Phytochemistry reviews 2007-04, Vol.6 (1), p.197-201 |
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| creator | Erdemoglu, Nurgun Ozkan, Semiha Tosun, Fatma |
| description | Purpose of the present study was to evaluate alkaloid profile of the aerial parts of Lupinus angustifolius growing in Turkey by capillary gas chromatography-mass spectrometry (GC-MS). Fifteen alkaloids were identified by capillary GC-MS. 13α-Hydroxylupanine (50.78%) and lupanine (23.55%) were determined as the main alkaloids in the aerial parts of L. angustifolius. Ammodendrine, isoangustifoline, tetrahydrorhombifoline, angustifoline, α-isolupanine, 5,6-dehydrolupanine, 11,12-dehydrolupanine, 13α-acetoxylupanine, 13α-isovaleroyloxylupanine, 13α-valeroyloxylupanine, 13α-tigloyloxylupanine, 13α-cis-cinnamoyloxylupanine and 13α-cis-cinnamoyloxy-17-oxolupanine were identified as the minor alkaloids of the plant. Furthermore, antibacterial and antifungal activities of L. angustifolius alkaloid extract were tested against standard strains of the following bacteria; Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus as well as the fungi; Candida albicans and C. krusei. The alkaloid extract showed significant activity on B. subtilis, S. aureus and P. aeruginosa while it was weakly active on E. coli. On the other hand, the extract possessed moderate activity against C. albicans and C. krusei. |
| doi_str_mv | 10.1007/s11101-006-9055-8 |
| format | Article |
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Fifteen alkaloids were identified by capillary GC-MS. 13α-Hydroxylupanine (50.78%) and lupanine (23.55%) were determined as the main alkaloids in the aerial parts of L. angustifolius. Ammodendrine, isoangustifoline, tetrahydrorhombifoline, angustifoline, α-isolupanine, 5,6-dehydrolupanine, 11,12-dehydrolupanine, 13α-acetoxylupanine, 13α-isovaleroyloxylupanine, 13α-valeroyloxylupanine, 13α-tigloyloxylupanine, 13α-cis-cinnamoyloxylupanine and 13α-cis-cinnamoyloxy-17-oxolupanine were identified as the minor alkaloids of the plant. Furthermore, antibacterial and antifungal activities of L. angustifolius alkaloid extract were tested against standard strains of the following bacteria; Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus as well as the fungi; Candida albicans and C. krusei. The alkaloid extract showed significant activity on B. subtilis, S. aureus and P. aeruginosa while it was weakly active on E. coli. On the other hand, the extract possessed moderate activity against C. albicans and C. krusei.</description><identifier>ISSN: 1568-7767</identifier><identifier>EISSN: 1572-980X</identifier><identifier>DOI: 10.1007/s11101-006-9055-8</identifier><language>eng</language><publisher>Dordrecht: Dordrecht : Kluwer Academic Publishers</publisher><subject>Alkaloids ; Antifungal activity ; Antimicrobial activity ; Bacillus subtilis ; Candida albicans ; Candida krusei ; E coli ; Escherichia coli ; Fabaceae ; Fungi ; Fungicides ; Gas chromatography ; GC-MS ; Lupinus angustifolius ; Mass spectrometry ; Mass spectroscopy ; Pseudomonas aeruginosa ; Staphylococcus aureus</subject><ispartof>Phytochemistry reviews, 2007-04, Vol.6 (1), p.197-201</ispartof><rights>Phytochemistry Reviews is a copyright of Springer, (2007). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c243t-d0df5c54f44a473e9da2ad3402e77fb1627e045a0677e76e6cba61b2aab22ef13</citedby><cites>FETCH-LOGICAL-c243t-d0df5c54f44a473e9da2ad3402e77fb1627e045a0677e76e6cba61b2aab22ef13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Erdemoglu, Nurgun</creatorcontrib><creatorcontrib>Ozkan, Semiha</creatorcontrib><creatorcontrib>Tosun, Fatma</creatorcontrib><title>Alkaloid profile and antimicrobial activity of Lupinus angustifolius L. alkaloid extract</title><title>Phytochemistry reviews</title><description>Purpose of the present study was to evaluate alkaloid profile of the aerial parts of Lupinus angustifolius growing in Turkey by capillary gas chromatography-mass spectrometry (GC-MS). Fifteen alkaloids were identified by capillary GC-MS. 13α-Hydroxylupanine (50.78%) and lupanine (23.55%) were determined as the main alkaloids in the aerial parts of L. angustifolius. Ammodendrine, isoangustifoline, tetrahydrorhombifoline, angustifoline, α-isolupanine, 5,6-dehydrolupanine, 11,12-dehydrolupanine, 13α-acetoxylupanine, 13α-isovaleroyloxylupanine, 13α-valeroyloxylupanine, 13α-tigloyloxylupanine, 13α-cis-cinnamoyloxylupanine and 13α-cis-cinnamoyloxy-17-oxolupanine were identified as the minor alkaloids of the plant. Furthermore, antibacterial and antifungal activities of L. angustifolius alkaloid extract were tested against standard strains of the following bacteria; Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus as well as the fungi; Candida albicans and C. krusei. The alkaloid extract showed significant activity on B. subtilis, S. aureus and P. aeruginosa while it was weakly active on E. coli. On the other hand, the extract possessed moderate activity against C. albicans and C. krusei.</description><subject>Alkaloids</subject><subject>Antifungal activity</subject><subject>Antimicrobial activity</subject><subject>Bacillus subtilis</subject><subject>Candida albicans</subject><subject>Candida krusei</subject><subject>E coli</subject><subject>Escherichia coli</subject><subject>Fabaceae</subject><subject>Fungi</subject><subject>Fungicides</subject><subject>Gas chromatography</subject><subject>GC-MS</subject><subject>Lupinus angustifolius</subject><subject>Mass spectrometry</subject><subject>Mass spectroscopy</subject><subject>Pseudomonas aeruginosa</subject><subject>Staphylococcus aureus</subject><issn>1568-7767</issn><issn>1572-980X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpdkE9LxDAQxYMouK5-AE8WBG9dJ2mTNMdl8R8UPOjC3sK0TZas3XZtWnG_vSnVi4dhZuD3hjePkGsKCwog7z2lFGgMIGIFnMfZCZlRLlmsMticjrPIYimFPCcX3u8AGBWczchmWX9g3boqOnStdbWJsKlC9W7vyq4tHNYRlr37cv0xam2UDwfXDD4Q28H3zra1C1u-iPDvjvnuu6C4JGcWa2-ufvucrB8f3lfPcf769LJa5nHJ0qSPK6gsL3lq0xRTmRhVIcMqSYEZKW1BBZMGUo4gpDRSGFEWKGjBEAvGjKXJnNxNd4P_z8H4Xu-dL01dY2PawWuqpORZogJ4-w_ctUPXBG-aMa5SkEpmgaITFZ73vjNWHzq3x-6oKegxaT0lrUPSekxaj5qbSWOx1bjtnNfrNwY0CThXgqnkB_tOeyQ</recordid><startdate>200704</startdate><enddate>200704</enddate><creator>Erdemoglu, Nurgun</creator><creator>Ozkan, Semiha</creator><creator>Tosun, Fatma</creator><general>Dordrecht : Kluwer Academic Publishers</general><general>Springer Nature B.V</general><scope>FBQ</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X2</scope><scope>8FE</scope><scope>8FH</scope><scope>8FK</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M0K</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7QL</scope><scope>7QO</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>M7N</scope><scope>P64</scope></search><sort><creationdate>200704</creationdate><title>Alkaloid profile and antimicrobial activity of Lupinus angustifolius L. alkaloid extract</title><author>Erdemoglu, Nurgun ; Ozkan, Semiha ; Tosun, Fatma</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c243t-d0df5c54f44a473e9da2ad3402e77fb1627e045a0677e76e6cba61b2aab22ef13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Alkaloids</topic><topic>Antifungal activity</topic><topic>Antimicrobial activity</topic><topic>Bacillus subtilis</topic><topic>Candida albicans</topic><topic>Candida krusei</topic><topic>E coli</topic><topic>Escherichia coli</topic><topic>Fabaceae</topic><topic>Fungi</topic><topic>Fungicides</topic><topic>Gas chromatography</topic><topic>GC-MS</topic><topic>Lupinus angustifolius</topic><topic>Mass spectrometry</topic><topic>Mass spectroscopy</topic><topic>Pseudomonas aeruginosa</topic><topic>Staphylococcus aureus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Erdemoglu, Nurgun</creatorcontrib><creatorcontrib>Ozkan, Semiha</creatorcontrib><creatorcontrib>Tosun, Fatma</creatorcontrib><collection>AGRIS</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Agricultural Science Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Phytochemistry reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Erdemoglu, Nurgun</au><au>Ozkan, Semiha</au><au>Tosun, Fatma</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Alkaloid profile and antimicrobial activity of Lupinus angustifolius L. alkaloid extract</atitle><jtitle>Phytochemistry reviews</jtitle><date>2007-04</date><risdate>2007</risdate><volume>6</volume><issue>1</issue><spage>197</spage><epage>201</epage><pages>197-201</pages><issn>1568-7767</issn><eissn>1572-980X</eissn><abstract>Purpose of the present study was to evaluate alkaloid profile of the aerial parts of Lupinus angustifolius growing in Turkey by capillary gas chromatography-mass spectrometry (GC-MS). Fifteen alkaloids were identified by capillary GC-MS. 13α-Hydroxylupanine (50.78%) and lupanine (23.55%) were determined as the main alkaloids in the aerial parts of L. angustifolius. Ammodendrine, isoangustifoline, tetrahydrorhombifoline, angustifoline, α-isolupanine, 5,6-dehydrolupanine, 11,12-dehydrolupanine, 13α-acetoxylupanine, 13α-isovaleroyloxylupanine, 13α-valeroyloxylupanine, 13α-tigloyloxylupanine, 13α-cis-cinnamoyloxylupanine and 13α-cis-cinnamoyloxy-17-oxolupanine were identified as the minor alkaloids of the plant. Furthermore, antibacterial and antifungal activities of L. angustifolius alkaloid extract were tested against standard strains of the following bacteria; Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus as well as the fungi; Candida albicans and C. krusei. The alkaloid extract showed significant activity on B. subtilis, S. aureus and P. aeruginosa while it was weakly active on E. coli. 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| subjects | Alkaloids Antifungal activity Antimicrobial activity Bacillus subtilis Candida albicans Candida krusei E coli Escherichia coli Fabaceae Fungi Fungicides Gas chromatography GC-MS Lupinus angustifolius Mass spectrometry Mass spectroscopy Pseudomonas aeruginosa Staphylococcus aureus |
| title | Alkaloid profile and antimicrobial activity of Lupinus angustifolius L. alkaloid extract |
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