Human immunodeficiency virus-encoded Tat activates glycogen synthase kinase-3β to antagonize nuclear factor-κB survival pathway in neurons

The pathogenesis of human immunodeficiency virus type 1 (HIV‐1)‐associated dementia is mediated by neuronal dysfunction and death, brought about by the action of soluble neurotoxic factors that are released by virally infected macrophages and microglia. Paradoxically, many candidate HIV‐1 neurotoxin...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The European journal of neuroscience 2006-05, Vol.23 (10), p.2623-2634
Hauptverfasser:	Sui, Ziye, Sniderhan, Lynn F., Fan, Shongshan, Kazmierczak, Katarzyna, Reisinger, Elizabeth, Kovács, Attila D., Potash, Mary Jane, Dewhurst, Stephen, Gelbard, Harris A., Maggirwar, Sanjay B.
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis histone deacetylase human Human immunodeficiency virus 1 human immunodeficiency virus-ADA RelA
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!