Vaccinia Virus Complement Control Protein Ameliorates Collagen-Induced Arthritic Mice

The main objective of this study was to investigate the therapeutic efficiency of recombinant vaccinia virus complement control protein (rVCP) on collagen‐induced arthritis (CIA) in DBA‐1/J mice. Arthritis was induced in DBA‐1J mice by injecting bovine collagen emulsified in complete Freunds adjuvan...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2005-11, Vol.1056 (1), p.55-68
Hauptverfasser:	JHA, PURUSHOTTAM, SMITH, SCOTT A., JUSTUS, DAVID E., KOTWAL, GIRISH J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis - chemically induced Arthritis - drug therapy Arthritis - pathology Arthritis - physiopathology bone erosion Collagen collagen-induced arthritis complement control Disease Models, Animal Inflammation - prevention & control Injections, Intraperitoneal Male Mice Mice, Inbred DBA osteoclasts Recombinant Proteins - therapeutic use Vaccinia virus VCP Viral Proteins - administration & dosage Viral Proteins - genetics Viral Proteins - therapeutic use
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