N-terminal acetylation modulates Bax targeting to mitochondria

[Display omitted] The pro-apoptotic Bax protein is the main effector of mitochondrial permeabilization during apoptosis. Bax is controlled at several levels, including post-translational modifications such as phosphorylation and S-palmitoylation. However, little is known about the contribution of ot...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The international journal of biochemistry & cell biology 2018-02, Vol.95, p.35-42
Hauptverfasser:	Alves, Sara, Neiri, Leire, Chaves, Susana Rodrigues, Vieira, Selma, Trindade, Dário, Manon, Stephen, Dominguez, Veronica, Pintado, Belen, Jonckheere, Veronique, Van Damme, Petra, Silva, Rui Duarte, Aldabe, Rafael, Côrte-Real, Manuela
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Animals Apoptosis Bax bcl-2-Associated X Protein - chemistry bcl-2-Associated X Protein - genetics bcl-2-Associated X Protein - metabolism Cells, Cultured Crosses, Genetic Cytosol - enzymology Cytosol - metabolism Embryo, Mammalian - cytology Gene Deletion Humans Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Mitochondria Mitochondria - enzymology Mitochondria - metabolism N-terminal acetylation N-terminal acetyltransferase N-Terminal Acetyltransferase B - genetics N-Terminal Acetyltransferase B - metabolism NatB Protein Conformation Protein Processing, Post-Translational Protein Transport Recombinant Proteins - chemistry Recombinant Proteins - metabolism Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins - metabolism Substrate Specificity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!