Negative inotropic effects of diadenosine tetraphosphate are mediated by protein kinase C and phosphodiesterases stimulation in the rat heart

Extracellular diadenosine polyphosphates (ApnA) are recently considered as an endogenous signaling compounds with transmitter-like activity which present in numerous tissues, including heart. It has been demonstrated previously that extracellular ApnA cause alteration of the heart functioning via pu...

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Veröffentlicht in:	European journal of pharmacology 2018-02, Vol.820, p.97-105
Hauptverfasser:	Pakhomov, Nikolai, Pustovit, Ksenia, Potekhina, Victoria, Filatova, Tatiana, Kuzmin, Vladislav, Abramochkin, Denis
Format:	Artikel
Sprache:	eng
Schlagworte:	Diadenosine polyphosphates Heart Protein kinase C, phosphodiesterase, nitric oxide Purine receptors
Online-Zugang:	Volltext
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