Prolactin-releasing peptide improved leptin hypothalamic signaling in obese mice

The situation following anti-obesity drug termination is rarely investigated, eventhough a decrease in body weight needs to be sustained. Therefore, this study examined the impact of twice-daily peripheral administration of 5 mg/kg [N-palm-γGlu-Lys11] prolactin-releasing peptide 31 (palm11-PrRP31) i...

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Veröffentlicht in:	Journal of molecular endocrinology 2018-02, Vol.60 (2), p.85-94
Hauptverfasser:	Holubová, Martina, Hrubá, Lucie, Neprašová, Barbora, Majerčíková, Zuzana, Lacinová, Zdeňka, Kuneš, Jaroslav, Maletínská, Lenka, Železná, Blanka
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Apoptosis Body weight c-Jun protein Extracellular signal-regulated kinase Food intake FosB protein High fat diet Hypothalamus JNK protein Kinases Leptin Obesity Peptides Phosphorylation Potentiation Prolactin Prolactin-releasing peptide Rodents Solitary tract nucleus Transcription factors
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