The Wiskott–Aldrich syndrome protein (WASP) is essential for myoblast fusion in Drosophila

In higher organisms, mononucleated myoblasts fuse to form multinucleated myotubes. During this process, myoblasts undergo specific changes in cell morphology and cytoarchitecture. Previously, we have shown that the actin regulator Kette (Hem-2/Nap-1) is essential for myoblast fusion. In this study,...

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Veröffentlicht in:	Developmental biology 2007-04, Vol.304 (2), p.664-674
Hauptverfasser:	Schäfer, Gritt, Weber, Susanne, Holz, Anne, Bogdan, Sven, Schumacher, Sabine, Müller, Arno, Renkawitz-Pohl, Renate, Önel, Susanne-Filiz
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin cytoskeleton Alleles Animals cdc42 Cell Fusion Drosophila Drosophila - embryology Drosophila - metabolism Drosophila Proteins - genetics Drosophila Proteins - metabolism hem-2/nap-1 kette Microfilament Proteins - genetics Microfilament Proteins - metabolism Mutation Myoblast fusion Myoblasts - physiology Myogenesis wasp Wiskott-Aldrich Syndrome Protein - genetics Wiskott-Aldrich Syndrome Protein - metabolism
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