Clinical Strains of Chryseobacterium and Elizabethkingia spp. Isolated from Pediatric Patients in a University Hospital: Performance of MALDI-TOF MS-Based Identification, Antimicrobial Susceptibilities, and Baseline Patient Characteristics
Our objective was to evaluate the performance of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for identification of the Chryseobacterium and Elizabethkingia spp. isolated from pediatric patients at Hacettepe University Hospital using 16S rRNA gene seque...
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| Veröffentlicht in: | Microbial drug resistance (Larchmont, N.Y.) N.Y.), 2018-07, Vol.24 (6), p.816-821 |
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| creator | Mirza, Hasan Cenk Tuncer, Özlem Ölmez, Serpil Şener, Burçin Tuğcu, Gökçen Dilşa Özçelik, Uğur Gürsoy, Nafia Canan Otlu, Barış Büyükçam, Ayşe Kara, Ateş Sancak, Banu |
| description | Our objective was to evaluate the performance of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for identification of the
Chryseobacterium
and
Elizabethkingia
spp. isolated from pediatric patients at Hacettepe University Hospital using 16S rRNA gene sequencing as the gold standard and to determine the antimicrobial susceptibility patterns of the isolates and baseline characteristics of patients. All stored
Chryseobacterium
and
Elizabethkingia
spp. isolated from various clinical specimens (sputum, blood, and urine) of pediatric patients at Hacettepe University Hospital between 2012 and 2016 were included in this study. Minimum inhibitory concentrations of 10 antimicrobial agents were determined by Etest for all isolates. To determine the baseline characteristics of patients, medical records of all patients were retrospectively reviewed. In total, 18 isolates of
Chryseobacterium
spp. (16
C. indologenes
, 2
C. gleum
) and 5 isolates of
Elizabethkingia
spp. (3
E. meningoseptica
, 2
E. anophelis
) were identified by 16S rRNA sequencing. MALDI-TOF MS correctly identified 19 (82.6%) isolates to the species level. The quinolones (ciprofloxacin and levofloxacin), trimethoprim/sulfamethoxazole and piperacillin/tazobactam showed the highest spectrum of activity against the overall collection of isolates. Cystic fibrosis (CF) was the underlying disease in 81.8% of patients. To our knowledge, this study includes the largest number of
Chryseobacterium
spp. isolated from clinical specimens of pediatric patients in Turkey. In this study, we also report the first clinical isolate of
E. anophelis
in Turkey. Since, the majority of strains were isolated from patients with CF; larger, prospective clinical studies are needed to establish whether chryseobacteria could be considered as an emerging opportunistic pathogen in patients with CF. |
| doi_str_mv | 10.1089/mdr.2017.0206 |
| format | Article |
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Chryseobacterium
and
Elizabethkingia
spp. isolated from pediatric patients at Hacettepe University Hospital using 16S rRNA gene sequencing as the gold standard and to determine the antimicrobial susceptibility patterns of the isolates and baseline characteristics of patients. All stored
Chryseobacterium
and
Elizabethkingia
spp. isolated from various clinical specimens (sputum, blood, and urine) of pediatric patients at Hacettepe University Hospital between 2012 and 2016 were included in this study. Minimum inhibitory concentrations of 10 antimicrobial agents were determined by Etest for all isolates. To determine the baseline characteristics of patients, medical records of all patients were retrospectively reviewed. In total, 18 isolates of
Chryseobacterium
spp. (16
C. indologenes
, 2
C. gleum
) and 5 isolates of
Elizabethkingia
spp. (3
E. meningoseptica
, 2
E. anophelis
) were identified by 16S rRNA sequencing. MALDI-TOF MS correctly identified 19 (82.6%) isolates to the species level. The quinolones (ciprofloxacin and levofloxacin), trimethoprim/sulfamethoxazole and piperacillin/tazobactam showed the highest spectrum of activity against the overall collection of isolates. Cystic fibrosis (CF) was the underlying disease in 81.8% of patients. To our knowledge, this study includes the largest number of
Chryseobacterium
spp. isolated from clinical specimens of pediatric patients in Turkey. In this study, we also report the first clinical isolate of
E. anophelis
in Turkey. Since, the majority of strains were isolated from patients with CF; larger, prospective clinical studies are needed to establish whether chryseobacteria could be considered as an emerging opportunistic pathogen in patients with CF.</description><identifier>ISSN: 1076-6294</identifier><identifier>EISSN: 1931-8448</identifier><identifier>DOI: 10.1089/mdr.2017.0206</identifier><identifier>PMID: 29227188</identifier><language>eng</language><publisher>United States: Mary Ann Liebert, Inc</publisher><subject>Adolescent ; Anti-Bacterial Agents - therapeutic use ; Antiinfectives and antibacterials ; Antimicrobial agents ; Blood - microbiology ; Child ; Child, Preschool ; Chryseobacterium ; Chryseobacterium - drug effects ; Chryseobacterium - genetics ; Chryseobacterium - isolation & purification ; Ciprofloxacin ; Cystic fibrosis ; Desorption ; Epidemiology ; Female ; Gene sequencing ; Hospitals ; Hospitals, University ; Humans ; Identification ; Infant ; Infant, Newborn ; Infections ; Infectious diseases ; Ionization ; Ions ; Laboratories ; Lasers ; Levofloxacin ; Male ; Mass spectrometry ; Mass spectroscopy ; Medical records ; Medicine ; Meningitis ; Microbial Sensitivity Tests - methods ; Opportunist infection ; Patients ; Pediatrics ; Piperacillin ; Quinolones ; Retrospective Studies ; RNA, Ribosomal, 16S - genetics ; rRNA 16S ; Scientific imaging ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods ; Sputum ; Sputum - microbiology ; Sulfamethoxazole ; Tazobactam ; Trimethoprim ; Turkey ; University faculty ; Urine ; Urine - microbiology</subject><ispartof>Microbial drug resistance (Larchmont, N.Y.), 2018-07, Vol.24 (6), p.816-821</ispartof><rights>2018, Mary Ann Liebert, Inc.</rights><rights>(©) Copyright 2018, Mary Ann Liebert, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c365t-9f40799d00d0af13ac91e18855855870e8c508b42b3dea8ba0bba8be24fcbb593</citedby><cites>FETCH-LOGICAL-c365t-9f40799d00d0af13ac91e18855855870e8c508b42b3dea8ba0bba8be24fcbb593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29227188$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mirza, Hasan Cenk</creatorcontrib><creatorcontrib>Tuncer, Özlem</creatorcontrib><creatorcontrib>Ölmez, Serpil</creatorcontrib><creatorcontrib>Şener, Burçin</creatorcontrib><creatorcontrib>Tuğcu, Gökçen Dilşa</creatorcontrib><creatorcontrib>Özçelik, Uğur</creatorcontrib><creatorcontrib>Gürsoy, Nafia Canan</creatorcontrib><creatorcontrib>Otlu, Barış</creatorcontrib><creatorcontrib>Büyükçam, Ayşe</creatorcontrib><creatorcontrib>Kara, Ateş</creatorcontrib><creatorcontrib>Sancak, Banu</creatorcontrib><title>Clinical Strains of Chryseobacterium and Elizabethkingia spp. Isolated from Pediatric Patients in a University Hospital: Performance of MALDI-TOF MS-Based Identification, Antimicrobial Susceptibilities, and Baseline Patient Characteristics</title><title>Microbial drug resistance (Larchmont, N.Y.)</title><addtitle>Microb Drug Resist</addtitle><description>Our objective was to evaluate the performance of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for identification of the
Chryseobacterium
and
Elizabethkingia
spp. isolated from pediatric patients at Hacettepe University Hospital using 16S rRNA gene sequencing as the gold standard and to determine the antimicrobial susceptibility patterns of the isolates and baseline characteristics of patients. All stored
Chryseobacterium
and
Elizabethkingia
spp. isolated from various clinical specimens (sputum, blood, and urine) of pediatric patients at Hacettepe University Hospital between 2012 and 2016 were included in this study. Minimum inhibitory concentrations of 10 antimicrobial agents were determined by Etest for all isolates. To determine the baseline characteristics of patients, medical records of all patients were retrospectively reviewed. In total, 18 isolates of
Chryseobacterium
spp. (16
C. indologenes
, 2
C. gleum
) and 5 isolates of
Elizabethkingia
spp. (3
E. meningoseptica
, 2
E. anophelis
) were identified by 16S rRNA sequencing. MALDI-TOF MS correctly identified 19 (82.6%) isolates to the species level. The quinolones (ciprofloxacin and levofloxacin), trimethoprim/sulfamethoxazole and piperacillin/tazobactam showed the highest spectrum of activity against the overall collection of isolates. Cystic fibrosis (CF) was the underlying disease in 81.8% of patients. To our knowledge, this study includes the largest number of
Chryseobacterium
spp. isolated from clinical specimens of pediatric patients in Turkey. In this study, we also report the first clinical isolate of
E. anophelis
in Turkey. Since, the majority of strains were isolated from patients with CF; larger, prospective clinical studies are needed to establish whether chryseobacteria could be considered as an emerging opportunistic pathogen in patients with CF.</description><subject>Adolescent</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antiinfectives and antibacterials</subject><subject>Antimicrobial agents</subject><subject>Blood - microbiology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Chryseobacterium</subject><subject>Chryseobacterium - drug effects</subject><subject>Chryseobacterium - genetics</subject><subject>Chryseobacterium - isolation & purification</subject><subject>Ciprofloxacin</subject><subject>Cystic fibrosis</subject><subject>Desorption</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Gene sequencing</subject><subject>Hospitals</subject><subject>Hospitals, University</subject><subject>Humans</subject><subject>Identification</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Ionization</subject><subject>Ions</subject><subject>Laboratories</subject><subject>Lasers</subject><subject>Levofloxacin</subject><subject>Male</subject><subject>Mass spectrometry</subject><subject>Mass spectroscopy</subject><subject>Medical records</subject><subject>Medicine</subject><subject>Meningitis</subject><subject>Microbial Sensitivity Tests - methods</subject><subject>Opportunist infection</subject><subject>Patients</subject><subject>Pediatrics</subject><subject>Piperacillin</subject><subject>Quinolones</subject><subject>Retrospective Studies</subject><subject>RNA, Ribosomal, 16S - genetics</subject><subject>rRNA 16S</subject><subject>Scientific imaging</subject><subject>Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods</subject><subject>Sputum</subject><subject>Sputum - microbiology</subject><subject>Sulfamethoxazole</subject><subject>Tazobactam</subject><subject>Trimethoprim</subject><subject>Turkey</subject><subject>University faculty</subject><subject>Urine</subject><subject>Urine - microbiology</subject><issn>1076-6294</issn><issn>1931-8448</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFUk1v1DAQjRCIloUjV2SJC4dmsfNtbsvS0pW2aqW252jsTOiUxE5tL9Lyp_kLOGzLgQuSpbGt5zfveV6SvBV8KXgjP46dW2Zc1Eue8epZcixkLtKmKJrncc_rKq0yWRwlr7y_55yXospfJkeZzLJaNM1x8ms9kCENA7sODsh4Znu2vnN7j1aBDuhoNzIwHTsd6CcoDHffyXwjYH6almzj7QABO9Y7O7Ir7AiCI82uIBCa4BkZBuzW0A90nsKenVs_UYDhUwS73roRjMa558Vq-2WT3lyesYvr9DP4yLnpIgX1UV0ga07YKp5G0s4qmvXuvMYpkKKBYjN_8kfl_DI6wicF0Qu4gw8fSPvXyYseBo9vHusiuT07vVmfp9vLr5v1apvqvCpDKvuC11J2nHccepGDlgLjh5XlvGqOjS55o4pM5R1Co4ArFQtmRa-VKmW-SD4ceCdnH3boQztS1DsMYNDufCtkXZYyq8o6Qt__A723O2eiujYTPOdSyDi1RZIeUNG_9w77dnI0gtu3grdzEtqYhHZOQjsnIeLfPbLu1IjdX_TT6CMgPwDmazBmIFTown9ofwMW3MTe</recordid><startdate>20180701</startdate><enddate>20180701</enddate><creator>Mirza, Hasan Cenk</creator><creator>Tuncer, Özlem</creator><creator>Ölmez, Serpil</creator><creator>Şener, Burçin</creator><creator>Tuğcu, Gökçen Dilşa</creator><creator>Özçelik, Uğur</creator><creator>Gürsoy, Nafia Canan</creator><creator>Otlu, Barış</creator><creator>Büyükçam, Ayşe</creator><creator>Kara, Ateş</creator><creator>Sancak, Banu</creator><general>Mary Ann Liebert, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7T7</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20180701</creationdate><title>Clinical Strains of Chryseobacterium and Elizabethkingia spp. Isolated from Pediatric Patients in a University Hospital: Performance of MALDI-TOF MS-Based Identification, Antimicrobial Susceptibilities, and Baseline Patient Characteristics</title><author>Mirza, Hasan Cenk ; Tuncer, Özlem ; Ölmez, Serpil ; Şener, Burçin ; Tuğcu, Gökçen Dilşa ; Özçelik, Uğur ; Gürsoy, Nafia Canan ; Otlu, Barış ; Büyükçam, Ayşe ; Kara, Ateş ; Sancak, Banu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-9f40799d00d0af13ac91e18855855870e8c508b42b3dea8ba0bba8be24fcbb593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adolescent</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Antiinfectives and antibacterials</topic><topic>Antimicrobial agents</topic><topic>Blood - microbiology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Chryseobacterium</topic><topic>Chryseobacterium - drug effects</topic><topic>Chryseobacterium - genetics</topic><topic>Chryseobacterium - isolation & purification</topic><topic>Ciprofloxacin</topic><topic>Cystic fibrosis</topic><topic>Desorption</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Gene sequencing</topic><topic>Hospitals</topic><topic>Hospitals, University</topic><topic>Humans</topic><topic>Identification</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Infections</topic><topic>Infectious diseases</topic><topic>Ionization</topic><topic>Ions</topic><topic>Laboratories</topic><topic>Lasers</topic><topic>Levofloxacin</topic><topic>Male</topic><topic>Mass spectrometry</topic><topic>Mass spectroscopy</topic><topic>Medical records</topic><topic>Medicine</topic><topic>Meningitis</topic><topic>Microbial Sensitivity Tests - methods</topic><topic>Opportunist infection</topic><topic>Patients</topic><topic>Pediatrics</topic><topic>Piperacillin</topic><topic>Quinolones</topic><topic>Retrospective Studies</topic><topic>RNA, Ribosomal, 16S - genetics</topic><topic>rRNA 16S</topic><topic>Scientific imaging</topic><topic>Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods</topic><topic>Sputum</topic><topic>Sputum - microbiology</topic><topic>Sulfamethoxazole</topic><topic>Tazobactam</topic><topic>Trimethoprim</topic><topic>Turkey</topic><topic>University faculty</topic><topic>Urine</topic><topic>Urine - microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mirza, Hasan Cenk</creatorcontrib><creatorcontrib>Tuncer, Özlem</creatorcontrib><creatorcontrib>Ölmez, Serpil</creatorcontrib><creatorcontrib>Şener, Burçin</creatorcontrib><creatorcontrib>Tuğcu, Gökçen Dilşa</creatorcontrib><creatorcontrib>Özçelik, Uğur</creatorcontrib><creatorcontrib>Gürsoy, Nafia Canan</creatorcontrib><creatorcontrib>Otlu, Barış</creatorcontrib><creatorcontrib>Büyükçam, Ayşe</creatorcontrib><creatorcontrib>Kara, Ateş</creatorcontrib><creatorcontrib>Sancak, Banu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Microbial drug resistance (Larchmont, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mirza, Hasan Cenk</au><au>Tuncer, Özlem</au><au>Ölmez, Serpil</au><au>Şener, Burçin</au><au>Tuğcu, Gökçen Dilşa</au><au>Özçelik, Uğur</au><au>Gürsoy, Nafia Canan</au><au>Otlu, Barış</au><au>Büyükçam, Ayşe</au><au>Kara, Ateş</au><au>Sancak, Banu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical Strains of Chryseobacterium and Elizabethkingia spp. Isolated from Pediatric Patients in a University Hospital: Performance of MALDI-TOF MS-Based Identification, Antimicrobial Susceptibilities, and Baseline Patient Characteristics</atitle><jtitle>Microbial drug resistance (Larchmont, N.Y.)</jtitle><addtitle>Microb Drug Resist</addtitle><date>2018-07-01</date><risdate>2018</risdate><volume>24</volume><issue>6</issue><spage>816</spage><epage>821</epage><pages>816-821</pages><issn>1076-6294</issn><eissn>1931-8448</eissn><abstract>Our objective was to evaluate the performance of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for identification of the
Chryseobacterium
and
Elizabethkingia
spp. isolated from pediatric patients at Hacettepe University Hospital using 16S rRNA gene sequencing as the gold standard and to determine the antimicrobial susceptibility patterns of the isolates and baseline characteristics of patients. All stored
Chryseobacterium
and
Elizabethkingia
spp. isolated from various clinical specimens (sputum, blood, and urine) of pediatric patients at Hacettepe University Hospital between 2012 and 2016 were included in this study. Minimum inhibitory concentrations of 10 antimicrobial agents were determined by Etest for all isolates. To determine the baseline characteristics of patients, medical records of all patients were retrospectively reviewed. In total, 18 isolates of
Chryseobacterium
spp. (16
C. indologenes
, 2
C. gleum
) and 5 isolates of
Elizabethkingia
spp. (3
E. meningoseptica
, 2
E. anophelis
) were identified by 16S rRNA sequencing. MALDI-TOF MS correctly identified 19 (82.6%) isolates to the species level. The quinolones (ciprofloxacin and levofloxacin), trimethoprim/sulfamethoxazole and piperacillin/tazobactam showed the highest spectrum of activity against the overall collection of isolates. Cystic fibrosis (CF) was the underlying disease in 81.8% of patients. To our knowledge, this study includes the largest number of
Chryseobacterium
spp. isolated from clinical specimens of pediatric patients in Turkey. In this study, we also report the first clinical isolate of
E. anophelis
in Turkey. Since, the majority of strains were isolated from patients with CF; larger, prospective clinical studies are needed to establish whether chryseobacteria could be considered as an emerging opportunistic pathogen in patients with CF.</abstract><cop>United States</cop><pub>Mary Ann Liebert, Inc</pub><pmid>29227188</pmid><doi>10.1089/mdr.2017.0206</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1076-6294 |
| ispartof | Microbial drug resistance (Larchmont, N.Y.), 2018-07, Vol.24 (6), p.816-821 |
| issn | 1076-6294 1931-8448 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1975592657 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adolescent Anti-Bacterial Agents - therapeutic use Antiinfectives and antibacterials Antimicrobial agents Blood - microbiology Child Child, Preschool Chryseobacterium Chryseobacterium - drug effects Chryseobacterium - genetics Chryseobacterium - isolation & purification Ciprofloxacin Cystic fibrosis Desorption Epidemiology Female Gene sequencing Hospitals Hospitals, University Humans Identification Infant Infant, Newborn Infections Infectious diseases Ionization Ions Laboratories Lasers Levofloxacin Male Mass spectrometry Mass spectroscopy Medical records Medicine Meningitis Microbial Sensitivity Tests - methods Opportunist infection Patients Pediatrics Piperacillin Quinolones Retrospective Studies RNA, Ribosomal, 16S - genetics rRNA 16S Scientific imaging Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Sputum Sputum - microbiology Sulfamethoxazole Tazobactam Trimethoprim Turkey University faculty Urine Urine - microbiology |
| title | Clinical Strains of Chryseobacterium and Elizabethkingia spp. Isolated from Pediatric Patients in a University Hospital: Performance of MALDI-TOF MS-Based Identification, Antimicrobial Susceptibilities, and Baseline Patient Characteristics |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T09%3A29%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20Strains%20of%20Chryseobacterium%20and%20Elizabethkingia%20spp.%20Isolated%20from%20Pediatric%20Patients%20in%20a%20University%20Hospital:%20Performance%20of%20MALDI-TOF%20MS-Based%20Identification,%20Antimicrobial%20Susceptibilities,%20and%20Baseline%20Patient%20Characteristics&rft.jtitle=Microbial%20drug%20resistance%20(Larchmont,%20N.Y.)&rft.au=Mirza,%20Hasan%20Cenk&rft.date=2018-07-01&rft.volume=24&rft.issue=6&rft.spage=816&rft.epage=821&rft.pages=816-821&rft.issn=1076-6294&rft.eissn=1931-8448&rft_id=info:doi/10.1089/mdr.2017.0206&rft_dat=%3Cproquest_cross%3E1975592657%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2103091916&rft_id=info:pmid/29227188&rfr_iscdi=true |