Absence of veno-occlussive disease in a cohort of multiple myeloma patients undergoing autologous stem cell transplantation with targeted busulfan dosage

: Background: Plasma concentrations of oral busulfan (BU) were measured in multiple myeloma (MM) patients undergoing autologous peripheral blood stem cell transplantation (ASCT) with a double alkylating conditioning protocol in order to individualise doses of BU based on individual pharmacokinetic...

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Veröffentlicht in:	European journal of haematology 2006-07, Vol.77 (1), p.1-6
Hauptverfasser:	Clopés, A., Sureda, A., Sierra, J., Queraltó, J. M., Broto, A., Farré, R., Moreno, E., Brunet, S., Martino, R., Mangues, M. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged autologous stem cell transplantation Busulfan - administration & dosage Busulfan - blood Busulfan - pharmacokinetics Busulfan - toxicity Cause of Death Cohort Studies Drug Monitoring drug safety Female Hematopoietic Stem Cell Transplantation - methods Hepatic Veno-Occlusive Disease - etiology Hepatic Veno-Occlusive Disease - prevention & control Humans Incidence Male Middle Aged Mucositis - chemically induced multiple myeloma Multiple Myeloma - complications Multiple Myeloma - therapy oral busulfan pharmacokinetics Remission Induction Survival Rate Transplantation Conditioning - methods Transplantation, Autologous veno-occlusive disease
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