The challenge of testing chemicals for potential carcinogenicity using multiple short-term assays: An analysis of a proposed test battery for hair dyes

Recent reports of the association of hair dyes usage with increased bladder cancer risk in women with the slow NAT-2 acetylator phenotype have resulted both in attempts to identify the putative carcinogen as well as in devising batteries of tests that could be used to screen for such putative carcin...

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Veröffentlicht in:	Mutation research 2007-09, Vol.633 (1), p.55-66
Hauptverfasser:	Rosenkranz, Herbert S., Cunningham, Suzanne L., Mermelstein, Robert, Cunningham, Albert R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biological Assay Carcinogenicity Carcinogenicity Tests - methods Cells, Cultured - drug effects Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution Hair dyes Hair Dyes - chemistry Hair Dyes - classification Hair Dyes - toxicity Lymphoma - chemically induced Medical sciences Mice Micronucleus Tests Mutagenicity Tests - methods Predictive Value of Tests Salmonella typhimurium - drug effects Sensitivity and Specificity Short-term assays Test battery Toxicology
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