Impact of intratumoral heterogeneity of breast cancer tissue on quantitative metabolomics using high-resolution magic angle spinning 1 H NMR spectroscopy

High-resolution magic angle spinning (HR MAS) nuclear magnetic resonance (NMR) spectroscopy is increasingly being used to study metabolite levels in human breast cancer tissue, assessing, for instance, correlations with prognostic factors, survival outcome or therapeutic response. However, the impac...

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Veröffentlicht in:	NMR in biomedicine 2018-02, Vol.31 (2)
Hauptverfasser:	Gogiashvili, Mikheil, Horsch, Salome, Marchan, Rosemarie, Gianmoena, Kathrin, Cadenas, Cristina, Tanner, Berno, Naumann, Sabrina, Ersova, Diana, Lippek, Frank, Rahnenführer, Jörg, Andersson, Jan T, Hergenröder, Roland, Lambert, Jörg, Hengstler, Jan G, Edlund, Karolina
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Breast Neoplasms - diagnostic imaging Breast Neoplasms - metabolism Breast Neoplasms - pathology Female Humans Lipids - chemistry Metabolome Metabolomics Principal Component Analysis Proton Magnetic Resonance Spectroscopy - methods
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