Focused ultrasound subthalamotomy in patients with asymmetric Parkinson's disease: a pilot study

Ablative neurosurgery has been used to treat Parkinson's disease for many decades. MRI-guided focused ultrasound allows focal lesions to be made in deep brain structures without skull incision. We investigated the safety and preliminary efficacy of unilateral subthalamotomy by focused ultrasoun...

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Veröffentlicht in:	Lancet neurology 2018-01, Vol.17 (1), p.54-63
Hauptverfasser:	Martínez-Fernández, Raul, Rodríguez-Rojas, Rafael, del Álamo, Marta, Hernández-Fernández, Frida, Pineda-Pardo, Jose A, Dileone, Michele, Alonso-Frech, Fernando, Foffani, Guglielmo, Obeso, Ignacio, Gasca-Salas, Carmen, de Luis-Pastor, Esther, Vela, Lydia, Obeso, José A
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Adult Aged Ataxia Basal ganglia Blood pressure Brain research Central nervous system diseases Clinical trials Coronary artery disease Deep brain stimulation Drug withdrawal Drugs Dyskinesia Female Gait Heart diseases Hemorrhage Humans Hypertension Impulsive behavior Levodopa Magnetic Resonance Imaging Male Mental disorders Middle Aged Movement disorders Neurodegenerative diseases Neuronavigation - methods Neurosurgery NMR Nuclear magnetic resonance Outcome Assessment (Health Care) Parkinson Disease - diagnosis Parkinson Disease - surgery Parkinson's disease Patients Pilot Projects Postoperative Complications - physiopathology Postoperative Complications - psychology Psychiatry Skull Studies Subthalamic nucleus Subthalamic Nucleus - surgery Surgery Tremor (Muscular contraction) Ultrasonic imaging Ultrasonic Surgical Procedures - adverse effects Ultrasonic Surgical Procedures - methods Ultrasound
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