Thioredoxin-interacting protein deficiency ameliorates diabetic retinal angiogenesis

Diabetic retinopathy is the leading cause of blindness among working-aged adults around the world. Hyperglycemia and intraocular vascular endothelial growth factor (VEGF) over-accumulation are essential for the progression of diabetic retinopathy, which eventually results in proliferative diabetic r...

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Veröffentlicht in:	The international journal of biochemistry & cell biology 2018-01, Vol.94, p.61-70
Hauptverfasser:	Duan, Jialiang, Du, Chunyang, Shi, Yonghong, Liu, Danyan, Ma, Jingxue
Format:	Artikel
Sprache:	eng
Schlagworte:	Akt/mTOR Angiogenesis Proliferative diabetic retinopathy TXNIP VEGFR2
Online-Zugang:	Volltext
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