Pneumococci induced TLR- and Rac1-dependent NF-κB-recruitment to the IL-8 promoter in lung epithelial cells

Streptococcus pneumoniae is the major pathogen of community-acquired pneumonia. The respiratory epithelium constitutes the first line of defense against invading lung pathogens, including pneumococci. We analyzed the involvement of Toll-like receptors (TLR) and Rho-GTPase signaling in the activation...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2006-04, Vol.290 (4), p.L730-L737
Hauptverfasser:	Schmeck, Bernd, Huber, Sylvia, Moog, Kerstin, Zahlten, Janine, Hocke, Andreas C., Opitz, Bastian, Hammerschmidt, Sven, Mitchell, Tim J., Kracht, Michael, Rosseau, Simone, Suttorp, Norbert, Hippenstiel, Stefan
Format:	Artikel
Sprache:	eng
Schlagworte:	Streptococcus pneumoniae
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!