Nuclear interactions of topoisomerase II alpha and {szligbeta} with phospholipid scramblase 1

DNA topoisomerase (topo) II modulates DNA topology and is essential for cell division. There are two isoforms of topo II ( alpha and {szligbeta}) that have limited functional redundancy, although their catalytic mechanisms appear the same. Using their COOH-terminal domains (CTDs) in yeast two-hybrid...

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Veröffentlicht in:Nucleic acids research 2007-06, Vol.35 (12), p.4076-4085
Hauptverfasser: Wyles, Jessica P, Wu, Zhongqin, Mirski, Shelagh EL, Cole, Susan PC
Format: Artikel
Sprache:eng
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