TT232, A Novel Signal Transduction Inhibitory Compound in the Therapy of Cancer and Inflammatory Diseases

TT-232 is a structural analogue of somatostatin exhibiting strong and selective growth-inhibitory effects, inhibition of neurogenic inflammation, as well as general anti-inflammatory and analgesic potential without the wide-ranging endocrine side effects of the parent hormone and its "tradition...

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Veröffentlicht in:	Journal of receptors and signal transduction 2005, Vol.25 (4-6), p.217-235
Hauptverfasser:	SZOKOLÓCZI, ORSOLYA, SCHWAB, RICHÁRD, PETÁK, ISTVÁN, ÖRFI, LÁSZLÓ, PAP, ÁKOS, EBERLE, ALEX N., SZÜTS, TAMÁS, KÉRI1, GYÖRGY
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino Acids - chemistry Analogue Animals Anti-inflammatory Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Antineoplastic Agents - therapeutic use Apoptosis Apoptosis - physiology Cell Cycle - physiology Cell Line, Tumor Clinical trial Drug Screening Assays, Antitumor Enzyme Activation Enzyme Inhibitors - therapeutic use Humans Inflammation - drug therapy Inflammation - metabolism Molecular Sequence Data Molecular Structure Neoplasms - drug therapy Neoplasms - metabolism Neurogenic inflammation Peptides, Cyclic - genetics Peptides, Cyclic - therapeutic use Receptors, Somatostatin - metabolism Signal Transduction - physiology Signal transduction inhibitor Somatostatin Somatostatin - analogs & derivatives TT232
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