Activin A stimulates IκB-α/NFκB and rank expression for osteoclast differentiation, but not AKT survival pathway in osteoclast precursors

Recent studies have reported that activin A enhances osteoclastogenesis in cultures of mouse bone marrow cells stimulated with receptor activator of nuclear factor‐κB ligand (RANKL) and macrophage colony‐stimulating factor (M‐CSF). However, the exact mechanisms by which activin A functions during os...

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Veröffentlicht in:	Journal of cellular biochemistry 2003-09, Vol.90 (1), p.59-67
Hauptverfasser:	Sugatani, T., Alvarez, U.M., Hruska, K.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	activin A AKT mTOR NFκB osteoclast differentiation RANK survival
Online-Zugang:	Volltext
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