A moderate reduction of Bcl-X sub(L) expression protects against tumorigenesis; however, it also increases susceptibility to tissue injury

Little consideration has been given to the possibility that there could be variations in protein expression that alter susceptibility to tumorigenesis without causing other obvious phenotypic effects. Therefore, we sought to determine if haploinsufficiency for the antiapoptotic protein Bcl-X sub(L)...

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Veröffentlicht in:Oncogene 2005-10, Vol.24 (47), p.7120-7124
Hauptverfasser: Henderson, C C, Zhang, Z, Manson, SR, Riehm, J J, Kataoka, M, Flye, M W, Garbow, J R, You, M, Weintraub, S J
Format: Artikel
Sprache:eng
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