Efficacy and safety of levomilnacipran, vilazodone and vortioxetine compared with other second-generation antidepressants for major depressive disorder in adults: A systematic review and network meta-analysis

Second-generation antidepressants dominate the medical management of major depressive disorder (MDD). Levomilnacipran, vilazodone and vortioxetine are the latest therapeutic options approved for the treatment of MDD. This systematic review aims to compare the benefits and harms of vilazodone, levomi...

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Veröffentlicht in:	Journal of affective disorders 2018-03, Vol.228, p.1-12
Hauptverfasser:	Wagner, Gernot, Schultes, Marie-Therese, Titscher, Viktoria, Teufer, Birgit, Klerings, Irma, Gartlehner, Gerald
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antidepressive Agents, Second-Generation - adverse effects Antidepressive Agents, Second-Generation - therapeutic use Cyclopropanes - adverse effects Cyclopropanes - therapeutic use Depressive Disorder, Major - drug therapy Humans Levomilnacipran Network Meta-Analysis Piperazines - adverse effects Piperazines - therapeutic use Second-generation antidepressants Sulfides - adverse effects Sulfides - therapeutic use Systematic review Vilazodone Vilazodone Hydrochloride - adverse effects Vilazodone Hydrochloride - therapeutic use Vortioxetine
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