DNA damage induced by copper on erythrocytes of gilthead sea bream Sparus aurata and mollusk Scapharca inaequivalvis
Heavy metal pollution in rivers and its impact on aquatic ecosystems is a dynamic process. Fish are ideal indicators of heavy metal contamination in aquatic systems because they occupy different trophic levels and are of different sizes and ages. In particular, copper is an essential trace metal for...
Gespeichert in:
| Veröffentlicht in: | Archives of environmental contamination and toxicology 2003-10, Vol.45 (3), p.350-356 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 356 |
|---|---|
| container_issue | 3 |
| container_start_page | 350 |
| container_title | Archives of environmental contamination and toxicology |
| container_volume | 45 |
| creator | GABBIANELLI, Rosita LUPIDI, Giulio VILLARINI, Milena FALCIONI, Giancarlo |
| description | Heavy metal pollution in rivers and its impact on aquatic ecosystems is a dynamic process. Fish are ideal indicators of heavy metal contamination in aquatic systems because they occupy different trophic levels and are of different sizes and ages. In particular, copper is an essential trace metal for living organisms and it is present in all natural waters and sediments. In this paper, we report data on the effect of copper on DNA erythrocytes from the teleost gilthead sea bream Sparus aurata and the bivalve mollusk Scapharca inaequivalvis. In particular, the effect of 0.1 ppm of Cu2+ on the nucleated erythrocytes was analyzed using the "comet assay." This test is a promising tool for estimation of DNA damage at the single cell level. The data obtained show that the in vivo treatment with 0.1 ppm of copper increased the susceptibility of DNA to be damaged. Exposure to Cu2+ produces a more evident effect on Sparus aurata, as all three comet parameters significantly increased (tail length, tail intensity, and tail moment). The higher comet parameters measured in Scapharca inaequivalvis compared to Sparus aurata could be due to the difference in stability of the respective hemoglobins. The comet assay could represent a useful test to evaluate the biological consequences of environmental contamination by metals on marine organisms. |
| doi_str_mv | 10.1007/s00244-003-2171-1 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_19721904</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>19721904</sourcerecordid><originalsourceid>FETCH-LOGICAL-c385t-5bdee973f299398afe1dc26e268aa16e7697a945a6a77382b64cd8bbf76d0efe3</originalsourceid><addsrcrecordid>eNpdkUtr3DAURkVpSSZpfkA3RRTanVu9rMcyJG1aCM0i7VpcS9cZp7blSHZg_n08zECgq7s53-HCIeQDZ185Y-ZbYUwoVTEmK8ENr_gbsuFKiooZJt-SDWOOVUoqfkrOSnlkjAtr1Qk55UobVVu7IfP170saYYAHpN0Yl4CRNjsa0jRhpmmkmHfzNqewm7HQ1NKHrp-3CJEWBNpkhIHeT5CXQmHJMAOFMdIh9f1S_tH7ANMWcoDVDfi0dM_QP3flPXnXQl_w4njPyd8f3_9c_axu725-XV3eVkHaeq7qJiI6I1vhnHQWWuQxCI1CWwCu0WhnwKkaNBgjrWi0CtE2TWt0ZNiiPCdfDt4pp6cFy-yHrgTsexgxLcVzZwR3TK3gp__Ax7Tkcf3NG8lr5Wq9h_gBCjmVkrH1U-4GyDvPmd_38Icefu3h9z08Xzcfj-KlGTC-Lo4BVuDzEYASoG8zjKErr1zNXW1qJ18Afv-T4g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>731549564</pqid></control><display><type>article</type><title>DNA damage induced by copper on erythrocytes of gilthead sea bream Sparus aurata and mollusk Scapharca inaequivalvis</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>GABBIANELLI, Rosita ; LUPIDI, Giulio ; VILLARINI, Milena ; FALCIONI, Giancarlo</creator><creatorcontrib>GABBIANELLI, Rosita ; LUPIDI, Giulio ; VILLARINI, Milena ; FALCIONI, Giancarlo</creatorcontrib><description>Heavy metal pollution in rivers and its impact on aquatic ecosystems is a dynamic process. Fish are ideal indicators of heavy metal contamination in aquatic systems because they occupy different trophic levels and are of different sizes and ages. In particular, copper is an essential trace metal for living organisms and it is present in all natural waters and sediments. In this paper, we report data on the effect of copper on DNA erythrocytes from the teleost gilthead sea bream Sparus aurata and the bivalve mollusk Scapharca inaequivalvis. In particular, the effect of 0.1 ppm of Cu2+ on the nucleated erythrocytes was analyzed using the "comet assay." This test is a promising tool for estimation of DNA damage at the single cell level. The data obtained show that the in vivo treatment with 0.1 ppm of copper increased the susceptibility of DNA to be damaged. Exposure to Cu2+ produces a more evident effect on Sparus aurata, as all three comet parameters significantly increased (tail length, tail intensity, and tail moment). The higher comet parameters measured in Scapharca inaequivalvis compared to Sparus aurata could be due to the difference in stability of the respective hemoglobins. The comet assay could represent a useful test to evaluate the biological consequences of environmental contamination by metals on marine organisms.</description><identifier>ISSN: 0090-4341</identifier><identifier>EISSN: 1432-0703</identifier><identifier>DOI: 10.1007/s00244-003-2171-1</identifier><identifier>PMID: 14674588</identifier><identifier>CODEN: AECTCV</identifier><language>eng</language><publisher>Heidelberg: Springer-Verlag</publisher><subject>Agnatha. Pisces ; Animal, plant and microbial ecology ; Animals ; Applied ecology ; Aquaculture ; Aquatic ecosystems ; Aquatic environment ; Bioassays ; Biological and medical sciences ; Bivalvia ; Copper ; Copper - toxicity ; Deoxyribonucleic acid ; DNA ; DNA Damage ; Ecotoxicology, biological effects of pollution ; Effects of pollution and side effects of pesticides on vertebrates ; Erythrocytes ; Fish ; Fundamental and applied biological sciences. Psychology ; Heavy metals ; Marine ; Marine organisms ; Marine pollution ; Mollusca ; Mollusca - genetics ; Mollusca - physiology ; Mollusks ; Natural waters ; Scapharca inaequivalvis ; Sea Bream - genetics ; Sea Bream - physiology ; Shellfish ; Sparus aurata ; Techniques ; Teleostei ; Trace metals ; Trophic levels ; Water Pollutants - toxicity ; Water pollution</subject><ispartof>Archives of environmental contamination and toxicology, 2003-10, Vol.45 (3), p.350-356</ispartof><rights>2004 INIST-CNRS</rights><rights>Springer-Verlag New York Inc. 2003</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c385t-5bdee973f299398afe1dc26e268aa16e7697a945a6a77382b64cd8bbf76d0efe3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15195759$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14674588$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>GABBIANELLI, Rosita</creatorcontrib><creatorcontrib>LUPIDI, Giulio</creatorcontrib><creatorcontrib>VILLARINI, Milena</creatorcontrib><creatorcontrib>FALCIONI, Giancarlo</creatorcontrib><title>DNA damage induced by copper on erythrocytes of gilthead sea bream Sparus aurata and mollusk Scapharca inaequivalvis</title><title>Archives of environmental contamination and toxicology</title><addtitle>Arch Environ Contam Toxicol</addtitle><description>Heavy metal pollution in rivers and its impact on aquatic ecosystems is a dynamic process. Fish are ideal indicators of heavy metal contamination in aquatic systems because they occupy different trophic levels and are of different sizes and ages. In particular, copper is an essential trace metal for living organisms and it is present in all natural waters and sediments. In this paper, we report data on the effect of copper on DNA erythrocytes from the teleost gilthead sea bream Sparus aurata and the bivalve mollusk Scapharca inaequivalvis. In particular, the effect of 0.1 ppm of Cu2+ on the nucleated erythrocytes was analyzed using the "comet assay." This test is a promising tool for estimation of DNA damage at the single cell level. The data obtained show that the in vivo treatment with 0.1 ppm of copper increased the susceptibility of DNA to be damaged. Exposure to Cu2+ produces a more evident effect on Sparus aurata, as all three comet parameters significantly increased (tail length, tail intensity, and tail moment). The higher comet parameters measured in Scapharca inaequivalvis compared to Sparus aurata could be due to the difference in stability of the respective hemoglobins. The comet assay could represent a useful test to evaluate the biological consequences of environmental contamination by metals on marine organisms.</description><subject>Agnatha. Pisces</subject><subject>Animal, plant and microbial ecology</subject><subject>Animals</subject><subject>Applied ecology</subject><subject>Aquaculture</subject><subject>Aquatic ecosystems</subject><subject>Aquatic environment</subject><subject>Bioassays</subject><subject>Biological and medical sciences</subject><subject>Bivalvia</subject><subject>Copper</subject><subject>Copper - toxicity</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA Damage</subject><subject>Ecotoxicology, biological effects of pollution</subject><subject>Effects of pollution and side effects of pesticides on vertebrates</subject><subject>Erythrocytes</subject><subject>Fish</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Heavy metals</subject><subject>Marine</subject><subject>Marine organisms</subject><subject>Marine pollution</subject><subject>Mollusca</subject><subject>Mollusca - genetics</subject><subject>Mollusca - physiology</subject><subject>Mollusks</subject><subject>Natural waters</subject><subject>Scapharca inaequivalvis</subject><subject>Sea Bream - genetics</subject><subject>Sea Bream - physiology</subject><subject>Shellfish</subject><subject>Sparus aurata</subject><subject>Techniques</subject><subject>Teleostei</subject><subject>Trace metals</subject><subject>Trophic levels</subject><subject>Water Pollutants - toxicity</subject><subject>Water pollution</subject><issn>0090-4341</issn><issn>1432-0703</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpdkUtr3DAURkVpSSZpfkA3RRTanVu9rMcyJG1aCM0i7VpcS9cZp7blSHZg_n08zECgq7s53-HCIeQDZ185Y-ZbYUwoVTEmK8ENr_gbsuFKiooZJt-SDWOOVUoqfkrOSnlkjAtr1Qk55UobVVu7IfP170saYYAHpN0Yl4CRNjsa0jRhpmmkmHfzNqewm7HQ1NKHrp-3CJEWBNpkhIHeT5CXQmHJMAOFMdIh9f1S_tH7ANMWcoDVDfi0dM_QP3flPXnXQl_w4njPyd8f3_9c_axu725-XV3eVkHaeq7qJiI6I1vhnHQWWuQxCI1CWwCu0WhnwKkaNBgjrWi0CtE2TWt0ZNiiPCdfDt4pp6cFy-yHrgTsexgxLcVzZwR3TK3gp__Ax7Tkcf3NG8lr5Wq9h_gBCjmVkrH1U-4GyDvPmd_38Icefu3h9z08Xzcfj-KlGTC-Lo4BVuDzEYASoG8zjKErr1zNXW1qJ18Afv-T4g</recordid><startdate>20031001</startdate><enddate>20031001</enddate><creator>GABBIANELLI, Rosita</creator><creator>LUPIDI, Giulio</creator><creator>VILLARINI, Milena</creator><creator>FALCIONI, Giancarlo</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T7</scope><scope>7TV</scope><scope>7U7</scope><scope>7WY</scope><scope>7WZ</scope><scope>7X7</scope><scope>7XB</scope><scope>87Z</scope><scope>88E</scope><scope>88I</scope><scope>8C1</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>F~G</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K60</scope><scope>K6~</scope><scope>K9.</scope><scope>L.-</scope><scope>M0C</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>P64</scope><scope>PATMY</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>7QH</scope><scope>7SN</scope><scope>7TN</scope><scope>7UA</scope><scope>F1W</scope><scope>H97</scope><scope>L.G</scope></search><sort><creationdate>20031001</creationdate><title>DNA damage induced by copper on erythrocytes of gilthead sea bream Sparus aurata and mollusk Scapharca inaequivalvis</title><author>GABBIANELLI, Rosita ; LUPIDI, Giulio ; VILLARINI, Milena ; FALCIONI, Giancarlo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c385t-5bdee973f299398afe1dc26e268aa16e7697a945a6a77382b64cd8bbf76d0efe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Agnatha. Pisces</topic><topic>Animal, plant and microbial ecology</topic><topic>Animals</topic><topic>Applied ecology</topic><topic>Aquaculture</topic><topic>Aquatic ecosystems</topic><topic>Aquatic environment</topic><topic>Bioassays</topic><topic>Biological and medical sciences</topic><topic>Bivalvia</topic><topic>Copper</topic><topic>Copper - toxicity</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>DNA Damage</topic><topic>Ecotoxicology, biological effects of pollution</topic><topic>Effects of pollution and side effects of pesticides on vertebrates</topic><topic>Erythrocytes</topic><topic>Fish</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Heavy metals</topic><topic>Marine</topic><topic>Marine organisms</topic><topic>Marine pollution</topic><topic>Mollusca</topic><topic>Mollusca - genetics</topic><topic>Mollusca - physiology</topic><topic>Mollusks</topic><topic>Natural waters</topic><topic>Scapharca inaequivalvis</topic><topic>Sea Bream - genetics</topic><topic>Sea Bream - physiology</topic><topic>Shellfish</topic><topic>Sparus aurata</topic><topic>Techniques</topic><topic>Teleostei</topic><topic>Trace metals</topic><topic>Trophic levels</topic><topic>Water Pollutants - toxicity</topic><topic>Water pollution</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>GABBIANELLI, Rosita</creatorcontrib><creatorcontrib>LUPIDI, Giulio</creatorcontrib><creatorcontrib>VILLARINI, Milena</creatorcontrib><creatorcontrib>FALCIONI, Giancarlo</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Pollution Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Access via ABI/INFORM (ProQuest)</collection><collection>ABI/INFORM Global (PDF only)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ABI/INFORM Global (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ABI/INFORM Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Business Premium Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Business Premium Collection (Alumni)</collection><collection>Health Research Premium Collection</collection><collection>ABI/INFORM Global (Corporate)</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Business Collection (Alumni Edition)</collection><collection>ProQuest Business Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ABI/INFORM Professional Advanced</collection><collection>ABI/INFORM Global</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>ProQuest One Business</collection><collection>ProQuest One Business (Alumni)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>Aqualine</collection><collection>Ecology Abstracts</collection><collection>Oceanic Abstracts</collection><collection>Water Resources Abstracts</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><jtitle>Archives of environmental contamination and toxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>GABBIANELLI, Rosita</au><au>LUPIDI, Giulio</au><au>VILLARINI, Milena</au><au>FALCIONI, Giancarlo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>DNA damage induced by copper on erythrocytes of gilthead sea bream Sparus aurata and mollusk Scapharca inaequivalvis</atitle><jtitle>Archives of environmental contamination and toxicology</jtitle><addtitle>Arch Environ Contam Toxicol</addtitle><date>2003-10-01</date><risdate>2003</risdate><volume>45</volume><issue>3</issue><spage>350</spage><epage>356</epage><pages>350-356</pages><issn>0090-4341</issn><eissn>1432-0703</eissn><coden>AECTCV</coden><abstract>Heavy metal pollution in rivers and its impact on aquatic ecosystems is a dynamic process. Fish are ideal indicators of heavy metal contamination in aquatic systems because they occupy different trophic levels and are of different sizes and ages. In particular, copper is an essential trace metal for living organisms and it is present in all natural waters and sediments. In this paper, we report data on the effect of copper on DNA erythrocytes from the teleost gilthead sea bream Sparus aurata and the bivalve mollusk Scapharca inaequivalvis. In particular, the effect of 0.1 ppm of Cu2+ on the nucleated erythrocytes was analyzed using the "comet assay." This test is a promising tool for estimation of DNA damage at the single cell level. The data obtained show that the in vivo treatment with 0.1 ppm of copper increased the susceptibility of DNA to be damaged. Exposure to Cu2+ produces a more evident effect on Sparus aurata, as all three comet parameters significantly increased (tail length, tail intensity, and tail moment). The higher comet parameters measured in Scapharca inaequivalvis compared to Sparus aurata could be due to the difference in stability of the respective hemoglobins. The comet assay could represent a useful test to evaluate the biological consequences of environmental contamination by metals on marine organisms.</abstract><cop>Heidelberg</cop><cop>Berlin</cop><cop>New York, NY</cop><pub>Springer-Verlag</pub><pmid>14674588</pmid><doi>10.1007/s00244-003-2171-1</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0090-4341 |
| ispartof | Archives of environmental contamination and toxicology, 2003-10, Vol.45 (3), p.350-356 |
| issn | 0090-4341 1432-0703 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_19721904 |
| source | MEDLINE; SpringerNature Journals |
| subjects | Agnatha. Pisces Animal, plant and microbial ecology Animals Applied ecology Aquaculture Aquatic ecosystems Aquatic environment Bioassays Biological and medical sciences Bivalvia Copper Copper - toxicity Deoxyribonucleic acid DNA DNA Damage Ecotoxicology, biological effects of pollution Effects of pollution and side effects of pesticides on vertebrates Erythrocytes Fish Fundamental and applied biological sciences. Psychology Heavy metals Marine Marine organisms Marine pollution Mollusca Mollusca - genetics Mollusca - physiology Mollusks Natural waters Scapharca inaequivalvis Sea Bream - genetics Sea Bream - physiology Shellfish Sparus aurata Techniques Teleostei Trace metals Trophic levels Water Pollutants - toxicity Water pollution |
| title | DNA damage induced by copper on erythrocytes of gilthead sea bream Sparus aurata and mollusk Scapharca inaequivalvis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-12T23%3A33%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=DNA%20damage%20induced%20by%20copper%20on%20erythrocytes%20of%20gilthead%20sea%20bream%20Sparus%20aurata%20and%20mollusk%20Scapharca%20inaequivalvis&rft.jtitle=Archives%20of%20environmental%20contamination%20and%20toxicology&rft.au=GABBIANELLI,%20Rosita&rft.date=2003-10-01&rft.volume=45&rft.issue=3&rft.spage=350&rft.epage=356&rft.pages=350-356&rft.issn=0090-4341&rft.eissn=1432-0703&rft.coden=AECTCV&rft_id=info:doi/10.1007/s00244-003-2171-1&rft_dat=%3Cproquest_cross%3E19721904%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=731549564&rft_id=info:pmid/14674588&rfr_iscdi=true |