Tetrachlorosilane catalyzed multicomponent one-step fusion of biopertinent pyrimidine heterocycles

Multicomponent one-step fusion of a variety of pharmacologically pertinent pyrimidine heterocycles has efficiently been achieved from their respective aldehydes, β-dicarbonyl compounds, and urea/thiourea in the presence of a catalytic amount of tetrachlorosilane in DMF/AN mixture at normal ambient t...

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Veröffentlicht in:Tetrahedron 2008-05, Vol.64 (22), p.5023-5031
Hauptverfasser: Ramalingan, Chennan, Kwak, Young-Woo
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container_title Tetrahedron
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creator Ramalingan, Chennan
Kwak, Young-Woo
description Multicomponent one-step fusion of a variety of pharmacologically pertinent pyrimidine heterocycles has efficiently been achieved from their respective aldehydes, β-dicarbonyl compounds, and urea/thiourea in the presence of a catalytic amount of tetrachlorosilane in DMF/AN mixture at normal ambient temperature. [Display omitted]
doi_str_mv 10.1016/j.tet.2008.03.078
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title Tetrachlorosilane catalyzed multicomponent one-step fusion of biopertinent pyrimidine heterocycles
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